Breast cancer—one term, many entities?
Breast cancer, rather than constituting a monolithic entity, comprises heterogeneous tumors
with different clinical characteristics, disease courses, and responses to specific treatments …
with different clinical characteristics, disease courses, and responses to specific treatments …
Insight into the heterogeneity of breast cancer through next-generation sequencing
HG Russnes, N Navin, J Hicks… - The Journal of …, 2011 - Am Soc Clin Investig
Rapid and sophisticated improvements in molecular analysis have allowed us to sequence
whole human genomes as well as cancer genomes, and the findings suggest that we may …
whole human genomes as well as cancer genomes, and the findings suggest that we may …
Personalized immunotherapy against several neuronal and brain tumors
S Kuttruff-coqui, T Weinschenk, J Fritsche… - US Patent …, 2021 - Google Patents
2014-11-12 Assigned to IMMATICS BIOTECHNOLOGIES GMBH reassignment IMMATICS
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
Genome-wide DNA methylation profiles in progression to in situand invasive carcinoma of the breast with impact on gene transcription and prognosis
Background Ductal carcinoma in situ (DCIS) of the breast is a precursor of invasive breast
carcinoma. DNA methylation alterations are thought to be an early event in progression of …
carcinoma. DNA methylation alterations are thought to be an early event in progression of …
Comparative pan-cancer DNA methylation analysis reveals cancer common and specific patterns
Abnormal DNA methylation is an important epigenetic regulator involving tumorigenesis.
Deciphering cancer common and specific DNA methylation patterns is essential for us to …
Deciphering cancer common and specific DNA methylation patterns is essential for us to …
DNA methylation–based immune response signature improves patient diagnosis in multiple cancers
BACKGROUND. The tumor immune response is increasingly associated with better clinical
outcomes in breast and other cancers. However, the evaluation of tumor-infiltrating …
outcomes in breast and other cancers. However, the evaluation of tumor-infiltrating …
Aberrant DNA methylation impacts gene expression and prognosis in breast cancer subtypes
B Győrffy, G Bottai, T Fleischer… - … journal of cancer, 2016 - Wiley Online Library
DNA methylation has a substantial impact on gene expression, affecting the prognosis of
breast cancer (BC) patients dependent on molecular subtypes. In this study, we investigated …
breast cancer (BC) patients dependent on molecular subtypes. In this study, we investigated …
Genome-wide methylation analysis identifies genes specific to breast cancer hormone receptor status and risk of recurrence
MJ Fackler, CB Umbricht, D Williams, P Argani… - Cancer research, 2011 - AACR
To better understand the biology of hormone receptor–positive and–negative breast cancer
and to identify methylated gene markers of disease progression, we carried out a genome …
and to identify methylated gene markers of disease progression, we carried out a genome …
DNA methylation at enhancers identifies distinct breast cancer lineages
Breast cancers exhibit genome-wide aberrant DNA methylation patterns. To investigate how
these affect the transcriptome and which changes are linked to transformation or …
these affect the transcriptome and which changes are linked to transformation or …
[HTML][HTML] Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes
K Holm, D Grabau, K Lövgren, S Aradottir… - Molecular …, 2012 - Elsevier
Polycomb repressive complex 2 (PRC2) and its core member enhancer of zeste homolog 2
(EZH2) mediate the epigenetic gene silencing mark: trimethylation of lysine 27 on histone 3 …
(EZH2) mediate the epigenetic gene silencing mark: trimethylation of lysine 27 on histone 3 …