Nanodiscs in membrane biochemistry and biophysics

IG Denisov, SG Sligar - Chemical reviews, 2017 - ACS Publications
Membrane proteins play a most important part in metabolism, signaling, cell motility,
transport, development, and many other biochemical and biophysical processes which …

Polymer nanodiscs and their bioanalytical potential

MD Farrelly, LL Martin, SH Thang - Chemistry–A European …, 2021 - Wiley Online Library
Membrane proteins (MPs) play a pivotal role in cellular function and are therefore
predominant pharmaceutical targets. Although detailed understanding of MP structure and …

SMALPs are not simply nanodiscs: the polymer-to-lipid ratios of fractionated SMALPs underline their heterogeneous nature

E Kamilar, J Bariwal, W Zheng, H Ma… - Biomacromolecules, 2023 - ACS Publications
Amphipathic styrene-maleic acid (SMA) copolymers directly solubilize biomembranes into
SMA-lipid particles, or SMALPs, that are often regarded as nanodiscs and hailed as a native …

Cytosolic lipid droplets as engineered organelles for production and accumulation of terpenoid biomaterials in leaves

R Sadre, P Kuo, J Chen, Y Yang, A Banerjee… - Nature …, 2019 - nature.com
Cytosolic lipid droplets are endoplasmic reticulum-derived organelles typically found in
seeds as reservoirs for physiological energy and carbon to fuel germination. Here, we report …

Approaches for increasing the electrocatalitic efficiency of cytochrome P450 3A4

VV Shumyantseva, PI Koroleva, TV Bulko, TV Shkel… - …, 2023 - Elsevier
The electrochemically driven cytochrome P450 reactions have great promise as drug
sensing device, new drug searching tool and bioreactor with broad synthetic application. In …

Self‐Assembly of Rod‐Coil Bottlebrush Copolymers into Degradable Nanodiscs with a UV‐Triggered Self‐Immolation Process

H Zeng, X Liang, DA Roberts… - Angewandte Chemie …, 2024 - Wiley Online Library
Polymer nanodiscs, especially with stimuli‐responsive features, represent an unexplored
frontier in the nanomaterial landscape. Such 2D nanomaterials are considered highly …

Voltage-gated electrocatalysis of efficient and selective methane oxidation by tricopper clusters under ambient conditions

YF Tsai, T Natarajan, ZH Lin, IK Tsai… - Journal of the …, 2022 - ACS Publications
Selective methane oxidation is difficult chemistry. Here we describe a strategy for the
electrocatalysis of selective methane oxidation by immobilizing tricopper catalysts on the …

Electrochemical profiling of plants

M Gandhi, K Amreen - Electrochem, 2022 - mdpi.com
The profiling, or fingerprinting, of distinct varieties of the Plantae kingdom is based on the
bioactive ingredients, which are systematically segregated to perform their detailed analysis …

Reconstituted discoidal high-density lipoproteins: Bioinspired nanodiscs with many unexpected applications

M Tsujita, A Wolska, DAP Gutmann… - Current atherosclerosis …, 2018 - Springer
Abstract Purpose of Review Summarize the initial discovery of discoidal high-density
lipoprotein (HDL) in human plasma and review more recent innovations that span the use of …

Direct observation of multiple conformational states in Cytochrome P450 oxidoreductase and their modulation by membrane environment and ionic strength

K Bavishi, D Li, S Eiersholt, EN Hooley, TC Petersen… - Scientific reports, 2018 - nature.com
Cytochrome P450 oxidoreductase (POR) is the primary electron donor in eukaryotic
cytochrome P450 (CYP) containing systems. A wealth of ensemble biophysical studies of …