Physiology of the pancreatic α-cell and glucagon secretion: role in glucose homeostasis and diabetes
Angiogenesis is an important component in the development of thyroid goitre. Vascular
endothelial growth factor (VEGF) represents a family of specific endothelial cell mitogens …
endothelial growth factor (VEGF) represents a family of specific endothelial cell mitogens …
A new hypothesis of modular glucocorticoid actions: steroid treatment of rheumatic diseases revisited.
F Buttgereit, M Wehling, GR Burmester - Arthritis and rheumatism, 1998 - europepmc.org
A comment on this article appears in" Further thoughts on the immunomodulatory role of
glucocorticoids: comment on the article by Buttgereit et al." Arthritis Rheum. 1999 Feb; 42 …
glucocorticoids: comment on the article by Buttgereit et al." Arthritis Rheum. 1999 Feb; 42 …
Effect of DMARDs on the immunogenicity of vaccines
Y van Sleen, KSM van der Geest… - Nature Reviews …, 2023 - nature.com
Vaccines are important for protecting individuals at increased risk of severe infections,
including patients undergoing DMARD therapy. However, DMARD therapy can also …
including patients undergoing DMARD therapy. However, DMARD therapy can also …
[PDF][PDF] Mechanisms of steroid action and resistance in inflammation: MAP kinase phosphatase 1: a novel mediator of biological effects of glucocorticoids
AR Clark - J Endocrinol, 2003 - researchgate.net
Synthetic glucocorticoids (GCs) potently inhibit the expression of pro-inflammatory genes
and are widely used in the treatment of inflammatory diseases. However, some patients are …
and are widely used in the treatment of inflammatory diseases. However, some patients are …
Regulation of apoptosis by the Ft1 protein, a new modulator of protein kinase B/Akt
I Remy, SW Michnick - Molecular and cellular biology, 2004 - Am Soc Microbiol
The serine/threonine kinase protein kinase B (PKB)/Akt plays a central role in many cellular
processes, including cell growth, glucose metabolism, and apoptosis. However, the …
processes, including cell growth, glucose metabolism, and apoptosis. However, the …
Regulation of leukocyte‐endothelial interactions by glucocorticoids
C Pitzalis, N Pipitone, M Perretti - … of the New York Academy of …, 2002 - Wiley Online Library
Glucocorticoids (GCs) are steroid molecules endowed with powerful anti‐inflammatory and
immunosuppressive properties. Traditionally, the anti‐inflammatory action of GC has been …
immunosuppressive properties. Traditionally, the anti‐inflammatory action of GC has been …
miRNA profiling discriminates types of rejection and injury in human renal allografts
J Wilflingseder, H Regele, P Perco, A Kainz… - …, 2013 - journals.lww.com
Background Increasing evidence accumulates on the central involvement of microRNAs
(miRNAs) in disease pathophysiology. We identified distinctly deregulated miRNAs in …
(miRNAs) in disease pathophysiology. We identified distinctly deregulated miRNAs in …
Identification of anti‐inflammatory drugs according to their capacity to suppress type‐1 and type‐2 T cell profiles
H Moed, TJ Stoof, DM Boorsma… - Clinical & …, 2004 - Wiley Online Library
Background Down‐regulation or modulation of T cell activity by immunosuppressive drugs is
an effective treatment in diseases where exaggerated T cell responses play a role. A primary …
an effective treatment in diseases where exaggerated T cell responses play a role. A primary …
JTE-607, a novel inflammatory cytokine synthesis inhibitor without immunosuppression, protects from endotoxin shock in mice
M Kakutani, K Takeuchi, I Waga, H Iwamura… - Inflammation …, 1999 - Springer
Objective and Design: We investigated the effect of a novel N-benzoyl-L-phenylalanine
derivative compound (JTE-607) on production of various cytokines and other immune …
derivative compound (JTE-607) on production of various cytokines and other immune …
CAR T cells and T cells phenotype and function are impacted by glucocorticoid exposure with different magnitude
T Poiret, S Vikberg, E Schoutrop, J Mattsson… - Journal of Translational …, 2024 - Springer
Background Chimeric antigen receptor (CAR) T cell therapy is associated with high risk of
adverse events. Glucocorticoids (GCs) are cornerstone in the management of high-grade …
adverse events. Glucocorticoids (GCs) are cornerstone in the management of high-grade …