Psychedelics in psychiatry: neuroplastic, immunomodulatory, and neurotransmitter mechanisms

A Inserra, D De Gregorio, G Gobbi, M Nader - Pharmacological Reviews, 2021 - Elsevier
Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …

Genetics factors in major depression disease

M Shadrina, EA Bondarenko, PA Slominsky - Frontiers in psychiatry, 2018 - frontiersin.org
Depressive disorders (DDs) are one of the most widespread forms of psychiatric pathology.
According to the World Health Organization, about 350 million people in the world are …

Child maltreatment and risk for psychopathology in childhood and adulthood

SR Jaffee - Annual review of clinical psychology, 2017 - annualreviews.org
Although rates of child maltreatment are declining, more than 600,000 children in the United
States are substantiated victims of abuse or neglect. The focus of this review is on the …

Executive functions

I Cristofori, S Cohen-Zimerman, J Grafman - Handbook of clinical neurology, 2019 - Elsevier
Executive functions (EFs) include high-order cognitive abilities such as working memory,
inhibitory control, cognitive flexibility, planning, reasoning, and problem solving. EFs enable …

Current research trends in early life stress and depression: Review of human studies on sensitive periods, gene–environment interactions, and epigenetics

C Heim, EB Binder - Experimental neurology, 2012 - Elsevier
Early life stress, such as childhood abuse, neglect and loss, is a well established major risk
factor for developing depressive disorders later in life. We here summarize and discuss …

[HTML][HTML] Dopamine, serotonin and impulsivity

JW Dalley, JP Roiser - Neuroscience, 2012 - Elsevier
Impulsive people have a strong urge to act without thinking. It is sometimes regarded as a
positive trait but rash impulsiveness is also widely present in clinical disorders such as …

Cognitive mechanisms of treatment in depression

JP Roiser, R Elliott, BJ Sahakian - Neuropsychopharmacology, 2012 - nature.com
Cognitive abnormalities are a core feature of depression, and biases toward negatively
toned emotional information are common, but are they a cause or a consequence of …

Emotion-based dispositions to rash action: positive and negative urgency.

MA Cyders, GT Smith - Psychological bulletin, 2008 - psycnet.apa.org
Under heightened emotional states, individuals are more inclined to engage in ill-
considered or rash actions than at other times. The authors present evidence for the …

Integrating evidence from neuroimaging and neuropsychological studies of obsessive-compulsive disorder: the orbitofronto-striatal model revisited

L Menzies, SR Chamberlain, AR Laird… - Neuroscience & …, 2008 - Elsevier
Obsessive-compulsive disorder (OCD) is a common, heritable and disabling
neuropsychiatric disorder. Theoretical models suggest that OCD is underpinned by …

The role of peer rejection in adolescent depression

B Platt, KC Kadosh, JYF Lau - Depression and anxiety, 2013 - Wiley Online Library
Adolescence is a period of major risk for depression, which is associated with negative
personal, social, and educational outcomes. Yet, in comparison to adult models of …