The intestinal microbiota is a complex community of bacteria, archaea, viruses, protists and
fungi,. Although the composition of bacterial constituents has been linked to immune …

Clostridioides difficile is the main causative agent of antibiotic-associated diarrhea (AAD) in
hospitals in the developed world. Both infected patients and asymptomatic colonized …

Antibiotic treatment can deplete the commensal bacteria of a patient's gut microbiota and,
paradoxically, increase their risk of subsequent infections. In allogeneic hematopoietic stem …

Gut microbiota represents a hidden treasure vault encompassing trillions of microorganisms
that inhabit the intestinal epithelial barrier of the host. In the past decade, numerous in-vitro …

Background Gram-negative bloodstream infections (BSIs) represent a significant
complication facing allogeneic hematopoietic cell transplant (allo-HCT) recipients, as a …

Fidaxomicin (Fdx) is widely used to treat Clostridioides difficile (Cdiff) infections, but the
molecular basis of its narrow-spectrum activity in the human gut microbiome remains …

Hematologic and oncologic patients with chemo-or immunotherapy-related
immunosuppression are at substantial risk for bacterial infections and Pneumocystis jirovecii …

Fecal microbiota transplantation (FMT) is a successful therapeutic strategy for treating
recurrent Clostridioides difficile infection. Despite remarkable efficacy, implementation of …

PURPOSE Gut microbiota injury in allogeneic hematopoietic cell transplantation (HCT)
recipients and patients with AML has been associated with adverse clinical outcomes …

Bacterial microbiota play a critical role in mediating local and systemic immunity, and shifts
in these microbial communities have been linked to impaired outcomes in critical illness …