Cyclic dipeptides, also know as diketopiperazines (DKP), the simplest cyclic forms of
peptides widespread in nature, are unsurpassed in their structural and bio-functional …

This study investigates the crystal structure, physicochemical properties, and
pharmacokinetic profile of Ethyl 2-amino-6-methyl-4, 5, 6, 7-tetrahydrothieno [2, 3-c] pyridine …

The crystal and molecular structure landscape of a new drug ticagrelor has been
investigated by using experimental and theoretical approach. The structures of this …

Short peptides have great potential as safe and effective anticancer drug leads. Herein, the
influence of short cyclic peptides containing the Pro-Pro-Phe-Phe sequence on patient …

The present work arose out of a desire to fundamentally understand the molecular geometry,
weak interactions, electron density delocalization, and chemical reactivity features of 1, 5 …

The antidiabetic drug gliclazide (GLZ) has a slow absorption rate and a low bioavailability
due to its poor solubility. GLZ is often prescribed along with an antihypertensive, as many …

We herein discuss the synthesis and characterization of a novel mononuclear cobalt (II)
complex Co II (TPBP)(HTMA) 2 with the N-donor ligands; hexamethylenetetramine HTMA …

Considering the increasing importance of cyclopropyl-containing peptide-derived
compounds in the pharmaceutical industry, herein, we report the crystal engineering of a …

Targeting the polyamine biosynthetic pathway by inhibiting ornithine decarboxylase (ODC)
is a powerful approach in the fight against diverse viruses, including SARS-CoV-2 …

The title compound, N-benzoyl-2′-hydroxy-3-methylisovaline, representing synthon
polymorphism, can be interesting inter alia from the point of view of modern supramolecular …