Background: Inflammatory bowel disease (IBD), once considered to be a Western disease,
is increasingly being reported from India and other Asian countries. The present review …

Epidemiological and clinical studies have suggested that the pathogenesis of inflammatory
bowel disease (IBD) is strongly influenced by genetic predisposition. Beyond the limitations …

Several large-scale genome-wide association studies genetically linked IRGM to Crohn's
disease and other inflammatory disorders in which the IRGM appears to have a protective …

At a time when complex diseases affect globally 280 million people and claim 14 million
lives every year, there is an urgent need to rapidly increase our knowledge into their …

There is rising incidence and prevalence of inflammatory bowel disease (IBD) in India
topping the Southeast Asian (SEA) countries. The common genes implicated in disease …

The success of transcriptome-wide association studies (TWAS) has led to substantial
research toward improving the predictive accuracy of its core component of genetically …

Hosts and microbes have co-evolved over millions of years. Inflammatory bowel diseases
(IBDs), including Crohn's disease (CD) and ulcerative colitis (UC), are chronic immune …

Methods A multicenter, cross-sectional, prospective registry was established across four
geographical zones of India. Adult patients with ulcerative colitis (UC) or Crohn's disease …

Crohn's disease (CD) represents a chronic inflammatory disorder of the intestinal tract.
Several susceptibility genes have been linked to CD, though their precise role in the …

It is known that ankylosing spondylitis (AS) and inflammatory bowel disease (IBD) shared a
common genetic component. The gist of current study is to assess the role of IBD-associated …