Nuclear ribonuclease (RNase) P is a ubiquitous essential ribonucleoprotein complex, one of
only two known RNA-based enzymes found in all three domains of life. The RNA component …

Abstract Ribonuclease P (RNase P) is a ubiquitous endonuclease that catalyses the
maturation of the 5′ end of transfer RNA (tRNA). Although it carries out a biochemically …

Ribonuclease (RNase) P is the universal ribozyme responsible for 5′-end tRNA
processing. We report the crystal structure of the Thermotoga maritima RNase P …

Even though Bacillus subtilis is one of the most studied organisms, no function has been
identified for about 20% of its proteins. Among these unknown proteins are several RNA-and …

Abstract Background: Polynucleotide phosphorylase (PNPase) is a polyribonucleotide
nucleotidyl transferase (EC 2.7. 7.8) that degrades mRNA in prokaryotes. Streptomyces …

Transfer RNA is an essential adapter molecule that is found across all three domains of life.
The primary role of transfer RNA resides in its critical involvement in the accurate translation …

ABSTRACT Ribonuclease P (RNase P) is an ancient and essential endonuclease that
catalyses the cleavage of the 5′ leader sequence from precursor tRNAs (pre-tRNAs). The …

The RNA subunits of RNase Ps of Archaea and eukaryotes have been thought to depend
fundamentally on protein for activity, unlike those of Bacteria that are capable of efficient …

INTRODUCTION Ribonuclease P (RNase P), a universal ribozyme that has been found in
organisms from all three domains of life, processes the 5′ end of transfer RNA (tRNA) …

For an enzyme functioning predominantly in a seemingly housekeeping role of 5′ tRNA
maturation, RNase P displays a remarkable diversity in subunit make-up across the three …