Neuropharmacology of brain-stimulation-evoked aggression

A Siegel, TAP Roeling, TR Gregg, MR Kruk - … & Biobehavioral Reviews, 1999 - Elsevier
Evidence is reviewed concerning the brain areas and neurotransmitters involved in
aggressive behavior in the cat and rodent. In the cat, two distinct neural circuits involving the …

Treatment options in alzheimer s disease: the GABA story

M Solas, E Puerta, MJ Ramirez - Current pharmaceutical …, 2015 - ingentaconnect.com
Alzheimer's disease (AD) is the most common form of dementia in the elderly. Research
focused on identifying compounds that restore cognition and memory in AD patients is a …

Fast positive feedback between the adrenocortical stress response and a brain mechanism involved in aggressive behavior.

MR Kruk, J Halasz, W Meelis, J Haller - Behavioral neuroscience, 2004 - psycnet.apa.org
Aggressive behavior induces an adrenocortical stress response, and sudden stressors often
precipitate violent behavior. Experiments in rats revealed a fast, mutual, positive feedback …

GABAergic function in Alzheimer's disease: evidence for dysfunction and potential as a therapeutic target for the treatment of behavioural and psychological symptoms …

KL Lanctôt, N Herrmann, P Mazzotta… - The Canadian …, 2004 - journals.sagepub.com
Alzheimer's disease (AD) is characterized by disruptions in multiple major neurotransmitters.
While many studies have attempted to establish whether GABA is disrupted in AD patients …

The neurobiology of abnormal manifestations of aggression—a review of hypothalamic mechanisms in cats, rodents, and humans

J Haller - Brain research bulletin, 2013 - Elsevier
Aggression research was for long dominated by the assumption that aggression-related
psychopathologies result from the excessive activation of aggression-promoting brain …

5-HT1B receptors and aggression: a review

B Olivier, R Van Oorschot - European journal of pharmacology, 2005 - Elsevier
The serotonergic (5-HT) system in the brain is involved in the modulation of offensive
aggressive behavior. The dogma that activity of the 5-HT system is inversely related to …

Anterior hypothalamic neural activation and neurochemical associations with aggression in pair‐bonded male prairie voles

KL Gobrogge, Y Liu, X Jia… - Journal of Comparative …, 2007 - Wiley Online Library
Male prairie voles (Microtus ochrogaster) display mating‐induced pair bonding indicated by
social affiliation with their female partners and aggression toward unfamiliar conspecifics. In …

Mouse grooming microstructure is a reliable anxiety marker bidirectionally sensitive to GABAergic drugs

AV Kalueff, P Tuohimaa - European journal of pharmacology, 2005 - Elsevier
Grooming is an important part of rodent behavioural repertoire, representing a complex
hierarchically ordered cephalo-caudal sequence of patterns sensitive to stress and various …

Hypothalamic control of conspecific self-defense

L Wang, V Talwar, T Osakada, A Kuang, Z Guo… - Cell reports, 2019 - cell.com
Active defense against a conspecific aggressor is essential for survival. Previous studies
revealed strong c-Fos expression in the ventrolateral part of the ventromedial hypothalamus …

The hypothalamus: cross-roads of endocrine and behavioural regulation in grooming and aggression

MR Kruk, KGC Westphal, AMM Van Erp… - Neuroscience & …, 1998 - Elsevier
Anatomical and functional studies show that the hypothalamus is at the junction of
mechanisms involved in the exploratory appraisal phase of behaviour and mechanisms …