Anti-Trypanosoma cruzi Properties of Sesquiterpene Lactones Isolated from Stevia spp.: In Vitro and In Silico Studies

J Borgo, OG Elso, J Gomez, M Coll, CAN Catalán… - Pharmaceutics, 2023 - mdpi.com
Stevia species (Asteraceae) have been a rich source of terpenoid compounds, mainly
sesquiterpene lactones, several of which show antiprotozoal activity. In the search for new …

Structural New Data for Mitochondrial Peroxiredoxin From Trypanosoma cruzi Show High Similarity With Human Peroxiredoxin 3: Repositioning Thiostrepton as …

L Rivera-Santiago, I Martínez… - Frontiers in Cellular …, 2022 - frontiersin.org
Trypanosoma cruzi, the causal agent of Chagas disease, has peroxiredoxins (PRXs)
expressed in all stages of the parasite and whose function is to detoxify oxidizing agents …

Trypanocidal and Anti-Inflammatory Effects of Three ent-Kaurane Diterpenoids from Gymnocoronis spilanthoides var. subcordata (Asteraceae)

MG Selener, J Borgo, MB Sarratea, MA Delfino… - Pharmaceutics, 2024 - mdpi.com
Chagas disease, caused by the protozoan Trypanosoma cruzi, affects 6–7 million people
worldwide. The dichloromethane extract obtained from the aerial parts of Gymnocoronis …

frontiers Frontiers in Cellular and Infection Microbiology ORIGINAL RESEARCH published: 05 July 2022

VG Duschak, FS Buckner, FM Dos Santos… - … disease novel drug …, 2023 - books.google.com
Chagas disease, caused by the hemoflagellate Trypanosoma cruzi, is considered a
neglected tropical disease due to the scarcity of safe and effective treatments 1. Current …