Peptide-based vaccines for tuberculosis
W Gong, C Pan, P Cheng, J Wang, G Zhao… - Frontiers in …, 2022 - frontiersin.org
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. As a
result of the coronavirus disease 2019 (COVID-19) pandemic, the global TB mortality rate in …
result of the coronavirus disease 2019 (COVID-19) pandemic, the global TB mortality rate in …
mRNA vaccines: a new opportunity for malaria, tuberculosis and HIV
L Matarazzo, PJG Bettencourt - Frontiers in Immunology, 2023 - frontiersin.org
The success of the first licensed mRNA-based vaccines against COVID-19 has created a
widespread interest on mRNA technology for vaccinology. As expected, the number of …
widespread interest on mRNA technology for vaccinology. As expected, the number of …
Novel In Silico mRNA vaccine design exploiting proteins of M. tuberculosis that modulates host immune responses by inducing epigenetic modifications
H Al Tbeishat - Scientific Reports, 2022 - nature.com
Tuberculosis is an airborne infectious disease caused by Mycobacterium tuberculosis. BCG
is the only approved vaccine. However, it has limited global efficacy. Pathogens could affect …
is the only approved vaccine. However, it has limited global efficacy. Pathogens could affect …
Encapsulation and assessment of therapeutic cargo in engineered exosomes: a systematic review
Z Chen, M Xiong, J Tian, D Song, S Duan… - Journal of …, 2024 - Springer
Exosomes are nanoscale extracellular vesicles secreted by cells and enclosed by a lipid
bilayer membrane containing various biologically active cargoes such as proteins, lipids …
bilayer membrane containing various biologically active cargoes such as proteins, lipids …
In silico Analysis of Peptide-Based Biomarkers for the Diagnosis and Prevention of Latent Tuberculosis Infection
P Cheng, L Wang, W Gong - Frontiers in microbiology, 2022 - frontiersin.org
Background Latent tuberculosis infection (LTBI) is the primary source of active tuberculosis
(ATB), but there are no specific methods for diagnosing and preventing LTBI. Methods …
(ATB), but there are no specific methods for diagnosing and preventing LTBI. Methods …
A comprehensive approach to developing a multi-epitope vaccine against Mycobacterium tuberculosis: from in silico design to in vitro immunization evaluation
F Jiang, Y Han, Y Liu, Y Xue, P Cheng, L Xiao… - Frontiers in …, 2023 - frontiersin.org
Introduction The Bacillus Calmette-Guérin (BCG) vaccine, currently used against
tuberculosis (TB), exhibits inconsistent efficacy, highlighting the need for more potent TB …
tuberculosis (TB), exhibits inconsistent efficacy, highlighting the need for more potent TB …
Immunoinformatics design of multivalent epitope vaccine against monkeypox virus and its variants using membrane-bound, enveloped, and extracellular proteins as …
Introduction The current monkeypox (MPX) outbreak, caused by the monkeypox virus
(MPXV), has turned into a global concern, with over 59,000 infection cases and 23 deaths …
(MPXV), has turned into a global concern, with over 59,000 infection cases and 23 deaths …
Reverse vaccinology approach for multi-epitope centered vaccine design against delta variant of the SARS-CoV-2
K Jalal, K Khan, Z Basharat, MN Abbas… - … Science and Pollution …, 2022 - Springer
The ongoing COVID-19 outbreak, initially identified in Wuhan, China, has impacted people
all over the globe and new variants of concern continue to threaten hundreds of thousands …
all over the globe and new variants of concern continue to threaten hundreds of thousands …
[HTML][HTML] In silico design of a promiscuous chimeric multi-epitope vaccine against Mycobacterium tuberculosis
BT Andongma, Y Huang, F Chen, Q Tang… - Computational and …, 2023 - Elsevier
Tuberculosis (TB) is a global health threat, killing approximately 1.5 million people each
year. The eradication of Mycobacterium tuberculosis, the main causative agent of TB, is …
year. The eradication of Mycobacterium tuberculosis, the main causative agent of TB, is …
Development and immunological evaluation of an mRNA-based vaccine targeting Naegleria fowleri for the treatment of primary amoebic meningoencephalitis
More than 95% of patients fall victim to primary amoebic meningoencephalitis (PAM), a fatal
disease attacking the central nervous system. Naegleria fowleri, a brain-eating …
disease attacking the central nervous system. Naegleria fowleri, a brain-eating …