Cancer is a general term for more than 100 unique malignancies in different organs of the
body. Each cancer type and subtype has its own unique genetic, epigenetic, and cellular …

Advances in functional genomics have led to discovery of a large group of previous
uncharacterized long non-coding RNAs (lncRNAs). Emerging evidence indicates that …

Protein-coding genes account for only a small part of the human genome, whereas the vast
majority of transcripts make up the non-coding RNAs including long non-coding RNAs …

Melanoma treatment with the BRAF V600E inhibitor vemurafenib provides therapeutic
benefits but the common emergence of drug resistance remains a challenge. We generated …

MicroRNAs typically function at the level of posttranscriptional gene silencing within the
cytoplasm; however, increasing evidence suggests that they may also function in nuclear …

MicroRNAs (miRNAs) have emerged as critical regulators of neuronal survival during
cerebral ischemia/reperfusion injury. Accumulating evidence has shown that miR-211 plays …

Micro-RNAs (miRNAs) are short, non-coding RNA species, thought to act primarily through
downregulation of target mRNA species with subsequent decrease in encoded proteins …

Amongst the various gynecological malignancies affecting female health globally, ovarian
cancer is one of the predominant and lethal among all. The identification and functional …

Abstract miR-211 expression in human oral squamous cell carcinoma (OSCC) has been
implicated in poor patient survival. To investigate the oncogenic roles of miR-211, we …

Long noncoding RNAs (lncRNAs) are rapidly emerging as important regulators of gene
expression in a wide variety of physiological and pathological cellular processes. In …