The key objective of vaccination is the induction of an effective pathogen-specific immune
response that leads to protection against infection and/or disease caused by that pathogen …

The ISCOMATRIX adjuvant has antigen delivery and presentation properties as well as
immunomodulatory capabilities, which combine to provide enhanced and accelerated …

Post-translational modification (PTM) of antigens provides an additional source of
specificities targeted by immune responses to tumors or pathogens, but identifying antigen …

Immune-based therapies for cancer are generating substantial interest because of the
success of immune checkpoint inhibitors. This study aimed to enhance anticancer immunity …

Recently, cancer immunotherapy has gained lots of attention to replace the current
chemoradiation approaches and multi-epitope cancer vaccines are manifesting as the next …

Abstract The Immune Epitope Database and Analysis Resource (IEDB) contains information
related to antibodies and T cells across an expansive scope of research fields (infectious …

Multiepitope cancer vaccines are announcing themselves as the future of melanoma
treatment. Herein, high immunogenic regions of transmembrane protein 31 (TMEM31) …

Tumor-specific T cell receptor (TCR) gene transfer enables specific and potent immune
targeting of tumor antigens. Due to the prevalence of the HLA-A2 MHC class I supertype in …

Immunoinformatics is an emergent branch of informatics science that long ago pullulated
from the tree of knowledge that is bioinformatics. It is a discipline which applies informatic …

With recent advances in the design and delivery of peptide-based therapeutics there has
been a growing interest in the use of peptides in vaccine design. Moreover, functional …