ERRα protein is stabilized by LSD1 in a demethylation-independent manner
J Carnesecchi, C Cerutti, JM Vanacker, C Forcet - PLoS One, 2017 - journals.plos.org
The LSD1 histone demethylase is highly expressed in breast tumors where it constitutes a
factor of poor prognosis and promotes traits of cancer aggressiveness such as cell …
factor of poor prognosis and promotes traits of cancer aggressiveness such as cell …
QSAR evaluations to unravel the structural features in lysine-specific histone demethylase 1A inhibitors for novel anticancer lead development supported by molecular …
RD Jawarkar, RL Bakal, N Mukherjee, A Ghosh… - Molecules, 2022 - mdpi.com
Using 84 structurally diverse and experimentally validated LSD1/KDM1A inhibitors,
quantitative structure–activity relationship (QSAR) models were built by OECD requirements …
quantitative structure–activity relationship (QSAR) models were built by OECD requirements …
Soft Tissue Ewing Sarcoma Cell Drug Resistance Revisited: A Systems Biology Approach
S Asfa, HI Toy, R Arshinchi Bonab… - International Journal of …, 2023 - mdpi.com
Ewing sarcoma is a rare type of cancer that develops in the bones and soft tissues. Drug
therapy represents an extensively used modality for the treatment of sarcomas. However …
therapy represents an extensively used modality for the treatment of sarcomas. However …
Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in …
V Coutinho Carneiro, IC de Abreu da Silva… - PLoS Neglected …, 2020 - journals.plos.org
Treatment and control of schistosomiasis still rely on only one effective drug, praziquantel
(PZQ) and, due to mass treatment, the increasing risk of selecting for schistosome strains …
(PZQ) and, due to mass treatment, the increasing risk of selecting for schistosome strains …
[PDF][PDF] de Abreu da Silva IC, Amaral MS, Pereira ASA, Silveira GO, Pires DdS, et al.(2020) Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces …
V Coutinho Carneiro - PLoS Negl Trop Dis, 2020 - iris.uniroma1.it
Abstract Treatment and control of schistosomiasis still rely on only one effective drug,
praziquantel (PZQ) and, due to mass treatment, the increasing risk of selecting for …
praziquantel (PZQ) and, due to mass treatment, the increasing risk of selecting for …