Multivalent interactions can be applied universally for a targeted strengthening of an
interaction between different interfaces or molecules. The binding partners form cooperative …

Nanocrystals are fundamental to modern science and technology. Mastery over the shape of
a nanocrystal enables control of its properties and enhancement of its usefulness for a given …

Current antisense oligonucleotide (ASO) therapies for the treatment of central nervous
system (CNS) disorders are performed through invasive administration, thereby placing a …

Forces to reckon with: Supramolecular complexes, such as the one shown, are normally
based on a combination of different interactions such as ion pairing, hydrogen bonds, and …

The lamprey holds the clue to the link between supramolecular self-assembly and allosteric
ligand binding. Chelate cooperativity in self-assembled structures results in denaturation …

Polymer therapeutics encompass polymer–protein conjugates, drug–polymer conjugates,
and supramolecular drug‐delivery systems. Numerous polymer–protein conjugates with …

“Nanoscience” is the emerging science of objects that are intermediate in size between the
largest molecules and the smallest structures that can be fabricated by current …

The self-assembly of triazacyclonane-functionalized thiols on the surface of nanosize gold
particles provides a facile entry to functional gold nanoparticles that, upon complexation with …

Cell‐surface receptors acquire information from the extracellular environment and
coordinate intracellular responses. Many receptors do not operate as individual entities, but …

The generation and/or optimization of lead compounds by combinatorial methods has
become widely accepted in medicinal chemistry, and is the subject of continued …