Acute respiratory distress syndrome: potential of therapeutic interventions effective in treating progression from COVID-19 to treat progression from other illnesses—a …
EJ Ragel, LK Harris… - BMJ Open Respiratory …, 2023 - bmjopenrespres.bmj.com
Background Acute respiratory distress syndrome (ARDS) is the most severe form of lung
injury, rendering gaseous exchange insufficient, leading to respiratory failure. Despite over …
injury, rendering gaseous exchange insufficient, leading to respiratory failure. Despite over …
NLRP3 Inflammasome Involvement in Heart, Liver, and Lung Diseases—A Lesson from Cytokine Storm Syndrome
C Napodano, V Carnazzo, V Basile, K Pocino… - International Journal of …, 2023 - mdpi.com
Inflammation and inflammasomes have been proposed as important regulators of the host–
microorganism interaction, playing a key role in morbidity and mortality due to the …
microorganism interaction, playing a key role in morbidity and mortality due to the …
New insights into the pathogenesis of SARS-CoV-2 during and after the COVID-19 pandemic
JJ Carvajal, V García-Castillo, SV Cuellar… - Frontiers in …, 2024 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the
respiratory distress condition known as COVID-19. This disease broadly affects several …
respiratory distress condition known as COVID-19. This disease broadly affects several …
[HTML][HTML] Ribociclib leverages phosphodiesterase 4 inhibition in the treatment of neutrophilic inflammation and acute respiratory distress syndrome
PJ Chen, SH Chen, YL Chen, YH Wang, CY Lin… - Journal of Advanced …, 2024 - Elsevier
Introduction Overwhelming neutrophil activation and oxidative stress significantly contribute
to acute respiratory distress syndrome (ARDS) pathogenesis. However, the potential of …
to acute respiratory distress syndrome (ARDS) pathogenesis. However, the potential of …
IRF1 Mediates Growth Arrest and the Induction of a Secretory Phenotype in Alveolar Epithelial Cells in Response to Inflammatory Cytokines IFNγ/TNFα
In COVID-19, cytokine release syndrome can cause severe lung tissue damage leading to
acute respiratory distress syndrome (ARDS). Here, we address the effects of IFNγ, TNFα, IL …
acute respiratory distress syndrome (ARDS). Here, we address the effects of IFNγ, TNFα, IL …
Dual Effects of 3-epi-betulin from Daphniphyllum glaucescens in Suppressing SARS-CoV-2-Induced Inflammation and Inhibiting Virus Entry
The continuous emergence of SARS-CoV-2 variants has led to a protracted global COVID-
19 pandemic with significant impacts on public health and global economy. While there are …
19 pandemic with significant impacts on public health and global economy. While there are …
Potential use of sodium glucose co-transporter 2 inhibitors during acute illness: a systematic review based on COVID-19
C Tisch, E Xourgia, A Exadaktylos, M Ziaka - Endocrine, 2024 - Springer
Objective SGLT-2i are increasingly recognized for their benefits in patients with
cardiometabolic risk factors. Additionally, emerging evidence suggests potential applications …
cardiometabolic risk factors. Additionally, emerging evidence suggests potential applications …
Identifying COVID‐19 subtypes by single‐sample gene set enrichemnt analysis and providing guidance for sensitive drug selection
N Xiong, Q Sun - Journal of Medical Virology, 2024 - Wiley Online Library
This study aimed at using single‐sample gene set enrichment analysis scores to cluster
naso/pharyngeal swab specimen samples from coronavirus disease 2019 (COVID‐19) …
naso/pharyngeal swab specimen samples from coronavirus disease 2019 (COVID‐19) …
Cytokine-Induced iNOS in A549 Alveolar Epithelial Cells: A Potential Role in COVID-19 Lung Pathology
Background. In COVID-19, an uncontrolled inflammatory response might worsen lung
damage, leading to acute respiratory distress syndrome (ARDS). Recent evidence points to …
damage, leading to acute respiratory distress syndrome (ARDS). Recent evidence points to …
Preclinical Study in Mouse Thymus and Thymocytes: Effects of Treatment with a Combination of Sodium Dichloroacetate and Sodium Valproate on Infectious …
D Stakišaitis, L Kapočius, E Kilimaitė, D Gečys… - Pharmaceutics, 2023 - mdpi.com
The research presents data from a preclinical study on the anti-inflammatory effects of a
sodium dichloroacetate and sodium valproate combination (DCA–VPA). The 2-week …
sodium dichloroacetate and sodium valproate combination (DCA–VPA). The 2-week …