The basic properties of gold nanoparticles and their applications in tumor diagnosis and treatment

X Bai, Y Wang, Z Song, Y Feng, Y Chen… - International journal of …, 2020 - mdpi.com
Gold nanoparticles (AuNPs) have been widely studied and applied in the field of tumor
diagnosis and treatment because of their special fundamental properties. In order to make …

Nanoparticle radio-enhancement: principles, progress and application to cancer treatment

Z Kuncic, S Lacombe - Physics in Medicine & Biology, 2018 - iopscience.iop.org
Enhancement of radiation effects by high-atomic number nanoparticles (NPs) has been
increasingly studied for its potential to improve radiotherapeutic efficacy. The underlying …

Size-tuning ionization to optimize gold nanoparticles for simultaneous enhanced CT imaging and radiotherapy

Y Dou, Y Guo, X Li, X Li, S Wang, L Wang, G Lv… - ACS …, 2016 - ACS Publications
Computed tomography (CT) contrast and radiosensitization usually increase with particle
sizes of gold nanoparticles (AuNPs), but there is a huge challenge to improve both by …

Engineering gold-based radiosensitizers for cancer radiotherapy

N Goswami, Z Luo, X Yuan, DT Leong, J Xie - Materials Horizons, 2017 - pubs.rsc.org
Radiotherapy remains a major modality in cancer therapy. The main goal of radiotherapy is
to shrink tumors and kill cancer cells by using high-energy radiation, such as X-rays and γ …

Roadmap to clinical use of gold nanoparticles for radiation sensitization

J Schuemann, R Berbeco, DB Chithrani, SH Cho… - International Journal of …, 2016 - Elsevier
The past decade has seen a dramatic increase in interest in the use of gold nanoparticles
(GNPs) as radiation sensitizers for radiation therapy. This interest was initially driven by their …

Implications on clinical scenario of gold nanoparticle radiosensitization in regards to photon energy, nanoparticle size, concentration and location

E Lechtman, N Chattopadhyay, Z Cai… - Physics in Medicine …, 2011 - iopscience.iop.org
Gold nanoparticle (AuNP) radiosensitization represents a novel approach to enhance the
effectiveness of ionizing radiation. Its efficiency varies widely with photon source energy and …

Comparing gold nano-particle enhanced radiotherapy with protons, megavoltage photons and kilovoltage photons: a Monte Carlo simulation

Y Lin, SJ McMahon, M Scarpelli… - Physics in Medicine …, 2014 - iopscience.iop.org
Gold nanoparticles (GNPs) have shown potential to be used as a radiosensitizer for
radiation therapy. Despite extensive research activity to study GNP radiosensitization using …

Effect of particle size on gamma radiation shielding property of gadolinium oxide dispersed epoxy resin matrix composite

R Li, Y Gu, Y Wang, Z Yang, M Li… - Materials Research …, 2017 - iopscience.iop.org
Epoxy resin matrix composites filled with dispersed micro and nano gadolinium oxide (Gd 2
O 3) particles of different contents were fabricated in this study. The γ radiation shielding and …

Radiosensitization by gold nanoparticles: Will they ever make it to the clinic?

L Cui, S Her, GR Borst, RG Bristow, DA Jaffray… - Radiotherapy and …, 2017 - Elsevier
The utilization of gold nanoparticles (AuNPs) as radiosensitizers has shown great promise in
pre-clinical research. In the current review, the physical, chemical, and biological pathways …

Targeted radiotherapy with gold nanoparticles: current status and future perspectives

W Ngwa, R Kumar, S Sridhar, H Korideck… - …, 2014 - Taylor & Francis
Radiation therapy (RT) is the treatment of cancer and other diseases with ionizing radiation.
The ultimate goal of RT is to destroy all the disease cells while sparing healthy tissue …