X-Linked intellectual disability (XLID) accounts for 5%–10% of intellectual disability in males.
Over 150 syndromes, the most common of which is the fragile X syndrome, have been …

The incidence of mental disability is 30% higher in males than in females. We have
examined entries in the OMIM database that are associated with mental disability and for …

A large French family including members affected by nonspecific X-linked mental
retardation, with or without autism or pervasive developmental disorder in affected male …

Physical mapping of the breakpoints of a pericentric inversion of the X chromosome (46, X,
inv [X][p21q27]) in a female patient with mild mental retardation revealed localization of the …

Abstract Affecting 1-3% of the population, mental retardation (MR) poses significant
challenges for clinicians and scientists. Understanding the biology of MR is complicated by …

Mutations in X-linked genes are likely to account for the observation that more males than
females are affected by mental retardation. Causative mutations have recently been …

Linkage analysis and DNA sequencing in a family exhibiting an X-linked mental retardation
(XLMR) syndrome, characterized by microcephaly, epilepsy, ataxia, and absent speech and …

Abstract Polyamines (putrescine, spermidine, spermine) are ubiquitous, simple molecules
that interact with a variety of other molecules in the cell, including nucleic acids …

Clinical data from 50 mentally retarded (MR) males in nine X-linked MR families, syndromic
and non-specific, with mutations (duplication, expansion, missense, and deletion mutations) …

X-linked mental retardation (XLMR) is a common cause of inherited intellectual disability
with an estimated prevalence of∼ 1/1000 males. Most XLMR conditions are inherited as X …