Horizontal gene transfer and adaptive evolution in bacteria

BJ Arnold, IT Huang, WP Hanage - Nature Reviews Microbiology, 2022 - nature.com
Horizontal gene transfer (HGT) is arguably the most conspicuous feature of bacterial
evolution. Evidence for HGT is found in most bacterial genomes. Although HGT can …

Antibiotic resistance genes in bacteria: Occurrence, spread, and control

Z Jian, L Zeng, T Xu, S Sun, S Yan… - Journal of basic …, 2021 - Wiley Online Library
The production and use of antibiotics are becoming increasingly common worldwide, and
the problem of antibiotic resistance is increasing alarmingly. Drug‐resistant infections …

Mutualistic interplay between bacteriophages and bacteria in the human gut

AN Shkoporov, CJ Turkington, C Hill - Nature Reviews Microbiology, 2022 - nature.com
Bacteriophages (phages) are often described as obligate predators of their bacterial hosts,
and phage predation is one of the leading forces controlling the density and distribution of …

Phage-mediated horizontal gene transfer and its implications for the human gut microbiome

T Borodovich, AN Shkoporov, RP Ross… - Gastroenterology …, 2022 - academic.oup.com
Horizontal gene transfer (HGT) in the microbiome has profound consequences for human
health and disease. The spread of antibiotic resistance genes, virulence, and pathogenicity …

Viruses defined by the position of the virosphere within the replicator space

EV Koonin, VV Dolja, M Krupovic… - … and Molecular Biology …, 2021 - Am Soc Microbiol
Originally, viruses were defined as miniscule infectious agents that passed through filters
that retain even the smallest cells. Subsequently, viruses were considered obligate …

Formation, development, and cross-species interactions in biofilms

A Luo, F Wang, D Sun, X Liu, B Xin - Frontiers in Microbiology, 2022 - frontiersin.org
Biofilms, which are essential vectors of bacterial survival, protect microbes from antibiotics
and host immune attack and are one of the leading causes that maintain drug-resistant …

Intrahost evolution of the gut microbiota

HC Barreto, I Gordo - Nature Reviews Microbiology, 2023 - nature.com
A massive number of microorganisms, belonging to different species, continuously divide
inside the guts of animals and humans. The large size of these communities and their rapid …

Major tail proteins of bacteriophages of the order Caudovirales

M Zinke, GF Schröder, A Lange - Journal of Biological Chemistry, 2022 - ASBMB
Technological advances in cryo-EM in recent years have given rise to detailed atomic
structures of bacteriophage tail tubes—a class of filamentous protein assemblies that could …

Structural atlas of a human gut crassvirus

OW Bayfield, AN Shkoporov, N Yutin, EV Khokhlova… - Nature, 2023 - nature.com
CrAssphage and related viruses of the order Crassvirales (hereafter referred to as
crassviruses) were originally discovered by cross-assembly of metagenomic sequences …

Structural basis of bacteriophage T5 infection trigger and E. coli cell wall perforation

R Linares, CA Arnaud, G Effantin, C Darnault… - Science …, 2023 - science.org
Most bacteriophages present a tail allowing host recognition, cell wall perforation, and viral
DNA channeling from the capsid to the infected bacterium cytoplasm. The majority of tailed …