Branched-chain amino acid (BCAA) catabolism has been considered to have an emerging
role in the pathogenesis of metabolic disturbances in obesity and type 2 diabetes (T2D) …

Metabolomics, or the comprehensive profiling of small molecule metabolites in cells, tissues,
or whole organisms, has undergone a rapid technological evolution in the past two decades …

Low-protein diets promote metabolic health in rodents and humans, and the benefits of low-
protein diets are recapitulated by specifically reducing dietary levels of the three branched …

Glycine is the proteinogenic amino-acid of lowest molecular weight, harboring a hydrogen
atom as a side-chain. In addition to being a building-block for proteins, glycine is also …

Branched-chain amino acids (BCAAs) are important nutrient signals that have direct and
indirect effects. Frequently, BCAAs have been reported to mediate antiobesity effects …

Insulin is required for maintenance of glucose homeostasis. Despite the importance of
insulin sensitivity to metabolic health, the mechanisms that induce insulin resistance remain …

The α, β polyunsaturated lipid aldehydes are potent lipid electrophiles that covalently modify
lipids, proteins, and nucleic acids. Recent work highlights the critical role these lipids play …

Branched-chain amino acids (BCAA) have increasingly been studied as playing a role in
diabetes, with the PubMed search string" diabetes" AND" branched chain amino acids" …

BACKGROUND Data from studies conducted in rodent models have shown that decreased
adipose tissue (AT) oxygenation is involved in the pathogenesis of obesity-induced insulin …

We aim to review the available literature on obese patients treated with bariatric procedures,
in order to assess their effect on the metabolic and gut microbiota profiles. A systematic …