Pain is an individualized experience for the person suffering from chronic pain. Significant
strides have been made in the last few decades in understanding various biological …

Introduction Chronic postsurgical pain (CPSP) is a prevalent condition that can diminish
health-related quality of life, cause functional deficits, and lead to patient distress. Rates of …

Background Chronic postsurgical pain (CPSP) in children remains an important problem
with no effective preventive or therapeutic strategies. Recently, genomic underpinnings …

Background Women undergoing breast cancer surgery frequently experience postsurgical
pain and fatigue, which reduces their quality of life. Although psychological factors have …

The exact mechanism underlies the development of neuropathic pain is not yet completely
understood. Mitogen and stress-activated kinase 1 (MSK-1) is an important downstream …

Chronic postsurgical pain (CPSP) affects a significant proportion of children and
adolescents after major surgery and is a detriment to both short-and long-term recovery …

Background Methods for identifying high‐pain responders undergoing total knee
arthroplasty remain important to improve individualized pain management. This study aimed …

Chronic pain is highly prevalent in the pediatric population. Many factors are involved in the
transition from acute to chronic pain. Currently, there are conceptual models proposed, but …

Background Vascular endothelial barrier disruption is pivotal in the development of acute
and chronic pain. Here, we demonstrate a previously unidentified molecular mechanism in …

Chronic postoperative pain is present in approximately 20% of patients undergoing total
knee arthroplasty. Studies indicate that pain mechanisms are associated with development …