Understanding immune responses to viral infections is crucial to progress in the quest for
effective infection prevention and control. The host immunity involves various mechanisms to …

The fight against infectious diseases calls for the development of safe and effective vaccines
that generate long-lasting protective immunity. In a few situations, vaccine-mediated immune …

Cancer immunotherapy has been regarded as the most significant scientific breakthrough of
2013, and antibody therapy is at the core of this breakthrough. Despite significant success …

Despite the significant progress in the recent efforts toward developing an effective vaccine
against toxoplasmosis, the search for new protective vaccination strategy still remains a …

Human norovirus is the leading cause of viral acute onset gastroenteritis disease burden,
with 685 million infections reported annually. Vulnerable populations, such as children …

Cellular immune responses are implicated in resistance to HIV and have been considered
for the development of an effective vaccine. Despite their safety profile, subunit vaccines …

Vaccines represent the discovery of utmost importance for global health, due to both
prophylactic action to prevent infections and therapeutic intervention in neoplastic diseases …

The identification of T cell epitopes derived from tumour specific antigens remains a
significant challenge for the development of peptide-based vaccines and immunotherapies …

We have applied our advanced multicanonical molecular dynamics (McMD)-based dynamic
docking methodology to investigate the binding mechanism of an HIV-1 Nef protein epitope …

The construction of artificial proteins using conservative B-cell and T-cell epitopes is
believed to be a promising approach for a vaccine design against diverse viral infections …