Synthesis of thiophene derivatives: Substituent effect, antioxidant activity, cyclic voltammetry, molecular docking, DFT, and TD-DFT calculations

N Uludag, G Serdaroğlu, P Sugumar… - Journal of Molecular …, 2022 - Elsevier
Abstract The efficient pathway 6-methyl-4, 5, 6, 7-tetrahydrobenzo [b] thiophene-3-
carboxylate derivatives have been synthesized. Due to the promising biochemical reactivity …

Antimicrobial activity, inhibition of biofilm formation, and molecular docking study of novel Ag-NHC complexes

N Şahin, E Üstün, U Tutar, C Celik, N Gürbüz… - Journal of …, 2021 - Elsevier
In this study, we reported the synthesis of a new series of Silver (I)-N-heterocyclic carbene
complexes which were obtained from the corresponding new N-heterocyclic carbene (NHC) …

New Hybrid (E)‐4‐((pyren‐1‐ylmethylene) amino)‐N‐(thiazol‐2‐yl) benzenesulfonamide as a Potential Drug Candidate: Spectroscopy, TD‐DFT, NBO, FMO, and MEP …

M Erdoğan, G Serdaroğlu - ChemistrySelect, 2021 - Wiley Online Library
A novel pyrene‐sulfathiazole‐based potential drug candidate 3 was designed, successfully
synthesized by a condensation reaction of pyrenecarboxaldehyde (1) with sulfathiazole (2) …

Spectral, thermal and DFT studies of novel nickel (II) complexes of 2-benzoylpyridine-N4-methyl-3-thiosemicarbazone: crystal structure of a square planar azido-nickel …

K Jayakumar, EB Seena, MRP Kurup, S Kaya… - Journal of Molecular …, 2022 - Elsevier
Novel six Ni (II) complexes of an NNS donor 2-benzoylpyridine-N 4-methyl-3-
thiosemicarbazone (HL) are synthesized and characterized. Various physicochemical …

Synthesis of Novel 1,3,4-Oxadiazole-Derived α-Aminophosphonates/α-Aminophosphonic Acids and Evaluation of Their In Vitro Antiviral Activity against the Avian …

S Hkiri, M Mekni-Toujani, E Üstün, K Hosni, A Ghram… - Pharmaceutics, 2022 - mdpi.com
An efficient and simple approach has been developed for the synthesis of eight dialkyl/aryl
[(5-phenyl-1, 3, 4-oxadiazol-2-ylamino)(aryl) methyl] phosphonates through the Pudovik …

DFT-based computations on some structurally related N-substituted piperazines

S Serin - Journal of the Indian Chemical Society, 2022 - Elsevier
In order to focus on more promising drug candidates by reducing the failures that occur in
the time-consuming and expensive discovery process of new drugs, it is highly efficient to …

Benzimidazol-2-ylidene Silver Complexes: Synthesis, Characterization, Antimicrobial and Antibiofilm Activities, Molecular Docking and Theoretical Investigations

U Tutar, C Çelik, E Üstün, N Özdemir, N Şahin… - Inorganics, 2023 - mdpi.com
Five silver (I) complexes, namely chloro [1-methallyl-3-benzyl) benzimidazol-2-ylidene]
silver (6), chloro [1-methallyl-3-(2, 3, 5, 6-tetramethylbenzyl) benzimidazol-2-ylidene] silver …

PEPPSI-Type Pd(II)—NHC Complexes on the Base of p-tert-Butylthiacalix[4]arene: Synthesis and Catalytic Activities

B Gafiatullin, A Akchurina, A Fedoseeva, E Sultanova… - Inorganics, 2023 - mdpi.com
The creation of effective catalytic systems for cross-coupling reactions, reduction, etc.,
capable of working in water-organic or pure aqueous media is in great demand. The article …

An efficient studies on C-2 cyanomethylation of the indole synthesis: The electronic and spectroscopic characterization (FT-IR, NMR, UV-Vis), antioxidant activity, and …

N Uludag, G Serdaroğlu - Journal of Molecular Structure, 2022 - Elsevier
The direct cynamethylation with the development of catalyzed methodologies directed to 2-
(cyanomethyl) indoles was reported by using tetrafluoro-1, 4-benzoquinone (TFB) as the …

Antioxidant activity, enzyme inhibition, electrochemical and theoretical evaluation of novel PEPPSI type N-heterocyclic carbene complexes

N Şahin, MS Celebi, MC Ayvaz - Inorganic Chemistry Communications, 2022 - Elsevier
N-Heterocyclic carbenes have attracted attention due to their strong sigma-donor and weak
pi-acceptor properties since they were first isolated. Pyridine is also found in many natural …