Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases
M Cargnello, PP Roux - Microbiology and molecular biology …, 2011 - Am Soc Microbiol
The mitogen-activated protein kinases (MAPKs) regulate diverse cellular programs by
relaying extracellular signals to intracellular responses. In mammals, there are more than a …
relaying extracellular signals to intracellular responses. In mammals, there are more than a …
[HTML][HTML] The MAPK cascades: signaling components, nuclear roles and mechanisms of nuclear translocation
The MAPK cascades are central signaling pathways that regulate a wide variety of
stimulated cellular processes, including proliferation, differentiation, apoptosis and stress …
stimulated cellular processes, including proliferation, differentiation, apoptosis and stress …
[HTML][HTML] The Ras/Raf/MEK/ERK signaling pathway and its role in the occurrence and development of HCC
L Li, GD Zhao, Z Shi, LL Qi, LY Zhou… - Oncology …, 2016 - spandidos-publications.com
Hepatocellular carcinoma (HCC) is the fifth most common tumor worldwide and has a very
poor prognosis. Its occurrence has been on the increase in recent years. Surgical resection …
poor prognosis. Its occurrence has been on the increase in recent years. Surgical resection …
Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions
G Pearson, F Robinson, T Beers Gibson, B Xu… - Endocrine …, 2001 - academic.oup.com
Mitogen-activated protein (MAP) kinases comprise a family of ubiquitous proline-directed,
protein-serine/threonine kinases, which participate in signal transduction pathways that …
protein-serine/threonine kinases, which participate in signal transduction pathways that …
How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer?
Y Mebratu, Y Tesfaigzi - Cell cycle, 2009 - Taylor & Francis
Extracellular signal-regulated protein kinases 1 and 2 (ERK1/2) are members of the mitogen-
activated protein kinase super family that can mediate cell proliferation and apoptosis. The …
activated protein kinase super family that can mediate cell proliferation and apoptosis. The …
ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions
Conserved signaling pathways that activate the mitogen-activated protein kinases (MAPKs)
are involved in relaying extracellular stimulations to intracellular responses. The MAPKs …
are involved in relaying extracellular stimulations to intracellular responses. The MAPKs …
Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human
Widmann, Christian, Spencer Gibson, Matthew B. Jarpe, and Gary L. Johnson. Mitogen-
Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human …
Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human …
Epidermal growth factor-related peptides and their receptors in human malignancies
DS Salomon, R Brandt, F Ciardiello… - Critical reviews in …, 1995 - Elsevier
The development of cancer is due to the accumulation of multiple somatic mutations and in
some cases due to germline mutations, which occur in malignancies such as retinoblastoma …
some cases due to germline mutations, which occur in malignancies such as retinoblastoma …
Rapid evolution of a protein in vitro by DNA shuffling
WPC Stemmer - Nature, 1994 - nature.com
DNA SHUFFLING is a method for in vitro homologous recombination of pools of selected
mutant genes by random fragmentation and polymerase chain reaction (PCR) reassembly1 …
mutant genes by random fragmentation and polymerase chain reaction (PCR) reassembly1 …
MAPK cascade signalling and synaptic plasticity
GM Thomas, RL Huganir - Nature Reviews Neuroscience, 2004 - nature.com
The mitogen-activated protein kinase (MAPK) cascade that leads to the activation of
extracellular signal-regulated kinases-1 and-2 (ERK1 and ERK2) has a key role in the …
extracellular signal-regulated kinases-1 and-2 (ERK1 and ERK2) has a key role in the …