Acute rheumatic fever (ARF) is the result of an autoimmune response to pharyngitis caused
by infection with group A Streptococcus. The long-term damage to cardiac valves caused by …

Autoimmune diseases are a range of diseases in which the immune response to self-
antigens results in damage or dysfunction of tissues. Autoimmune diseases can be systemic …

Streptococcus pyogenes, also known as group A Streptococcus (GAS), causes mild human
infections such as pharyngitis and impetigo and serious infections such as necrotizing …

Acute rheumatic fever is caused by an autoimmune response to throat infection with
Streptococcus pyogenes. Cardiac involvement during acute rheumatic fever can result in …

As a hallmark of autoimmune rheumatic diseases, autoantibodies have been used in
diagnosis for decades. However, the immunological mechanism underlying their generation …

Autoimmunity occurs when the immune system recognizes and attacks host tissue. In
addition to genetic factors, environmental triggers (in particular viruses, bacteria and other …

Autoimmunity can be triggered by many environmental factors, among which infectious
agents are pivotal. Here, we summarize current knowledge of the relationship between …

Opinion statement Early recognition of group A streptococcal pharyngitis and appropriate
management with benzathine penicillin using local clinical prediction rules together with …

The group A streptococcus, Streptococcus pyogenes, and its link to autoimmune sequelae,
has acquired a new level of understanding. Studies support the hypothesis that molecular …

Autoimmune diseases have registered an alarming rise worldwide in recent years.
Accumulated evidence indicates that the immune system′ s ability to distinguish self from …