High-risk oncogenic human cytomegalovirus

G Herbein - Viruses, 2022 - mdpi.com
Human cytomegalovirus (HCMV) is a herpesvirus that infects between 40% and 95% of the
population worldwide, usually without symptoms. The host immune response keeps the …

Tumors and cytomegalovirus: An intimate interplay

G Herbein - Viruses, 2022 - mdpi.com
Human cytomegalovirus (HCMV) is a herpesvirus that alternates lytic and latent infection,
infecting between 40 and 95% of the population worldwide, usually without symptoms …

A comprehensive proteogenomic pipeline for neoantigen discovery to advance personalized cancer immunotherapy

F Huber, M Arnaud, BJ Stevenson, J Michaux… - Nature …, 2024 - nature.com
The accurate identification and prioritization of antigenic peptides is crucial for the
development of personalized cancer immunotherapies. Publicly available pipelines to …

Human papillomavirus-encoded circular RNA circE7 promotes immune evasion in head and neck squamous cell carcinoma

J Ge, Y Meng, J Guo, P Chen, J Wang, L Shi… - Nature …, 2024 - nature.com
Immune evasion represents a crucial milestone in the progression of cancer and serves as
the theoretical foundation for tumor immunotherapy. In this study, we reveal a negative …

Epstein-Barr virus microRNAs in the pathogenesis of human cancers

BFR Caetano, BAS Jorge, BG Müller-Coan… - Cancer Letters, 2021 - Elsevier
Abstract The Epstein-Barr Virus (EBV) is a gamma-herpesvirus involved with a variety of
human cancers, notably the endemic Burkitt lymphoma and nasopharyngeal carcinoma. In …

EZH2-Myc Hallmark in Oncovirus/Cytomegalovirus Infections and Cytomegalovirus' Resemblance to Oncoviruses

R El Baba, G Herbein - Cells, 2024 - mdpi.com
Approximately 15–20% of global cancer cases are attributed to virus infections. Oncoviruses
employ various molecular strategies to enhance replication and persistence. Human …

Oncogenic viral infection and amino acid metabolism in cancer progression: Molecular insights and clinical implications

N Liu, F Shi, L Yang, W Liao, Y Cao - … et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
Viruses lack essential living system, so they must hijack host cell metabolism for its survival
and reproduction. Interestingly, the metabolic reprogramming induced by oncovirus is critical …

The role of microRNAs in the metastatic process of high-risk HPV-induced cancers

JMO Santos, S Peixoto da Silva, NR Costa… - Cancers, 2018 - mdpi.com
High-risk human papillomavirus (HPV)-driven cancers represent a major health concern
worldwide. Despite the constant effort to develop and promote vaccination against HPVs …

The AP‐1 pathway; A key regulator of cellular transformation modulated by oncogenic viruses

H Mirzaei, N Khodadad, C Karami… - Reviews in Medical …, 2020 - Wiley Online Library
Cancer progression is critically associated with modulation of host cell signaling pathways.
Activator protein‐1 (AP‐1) signaling is one such pathway whose deregulation renders the …

Viral Bcl2s' transmembrane domain interact with host Bcl2 proteins to control cellular apoptosis

MJ García-Murria, G Duart, B Grau… - Nature …, 2020 - nature.com
Viral control of programmed cell death relies in part on the expression of viral analogs of the
B-cell lymphoma 2 (Bcl2) protein known as viral Bcl2s (vBcl2s). vBcl2s control apoptosis by …