Multivariate analysis of ToF-SIMS data from multicomponent systems: the why, when, and how

DJ Graham, DG Castner - Biointerphases, 2012 - pubs.aip.org
The use of multivariate analysis (MVA) methods in the processing of time-of-flight secondary
ion mass spectrometry (ToF-SIMS) data has become increasingly more common. MVA …

High throughput screening for biomaterials discovery

MS Algahtani, DJ Scurr, AL Hook, DG Anderson… - Journal of Controlled …, 2014 - Elsevier
Using microarray technologies thousands of biomedical materials can be screened in a
rapid, parallel and cost effective fashion to identify the optimum candidate that fulfils a …

Exploring environmental sustainability through dimension reduction algorithms: A cost-effective UV spectroscopic method for simultaneous determination of veterinary …

MM Eraqi, AM Algohary, AM Ibrahim - Sustainable Chemistry and Pharmacy, 2024 - Elsevier
This study presents a cost-effective and environmentally friendly approach for the
simultaneous determination of a veterinary binary mixture comprising doxycycline …

Surface characterization of carbohydrate microarrays

DJ Scurr, T Horlacher, MA Oberli, DB Werz, L Kroeck… - Langmuir, 2010 - ACS Publications
Carbohydrate microarrays are essential tools to determine the biological function of glycans.
Here, we analyze a glycan array by time-of-flight secondary ion mass spectrometry (ToF …

ToF-SIMS analysis of chemical heterogenities in inkjet micro-array printed drug/polymer formulations

N Scoutaris, AL Hook, PR Gellert, CJ Roberts… - Journal of Materials …, 2012 - Springer
Three different formulations comprising two drugs, felodipine and hydrochlorothiazide (HCT)
and two polymers, poly (vinyl pyrolidone)(PVP) and poly (lactic-co-glycolic acid)(PLGA) …

Subcellular ToF-SIMS Imaging of the Snow Alga Sanguina nivaloides by Combining High Mass and High Lateral Resolution Acquisitions

C Seydoux, JA Ezzedine, GS Larbi, S Ravanel… - Analytical …, 2024 - ACS Publications
Time-of-flight secondary ion mass spectrometry (ToF-SIMS) imaging has demonstrated great
potential for metabolic imaging; however, achieving sufficiently high lateral and mass …

Imaging of crystalline and amorphous surface regions using time-of-flight secondary-ion mass spectrometry (ToF-SIMS): Application to pharmaceutical materials

A Iuras, DJ Scurr, C Boissier, ML Nicholas… - Analytical …, 2016 - ACS Publications
The structure of a material, in particular the extremes of crystalline and amorphous forms,
significantly impacts material performance in numerous sectors such as semiconductors …

Evaluation of blood adsorption onto dialysis membranes by time-of-flight secondary ion mass spectrometry and near-field infrared microscopy

S Aoyagi, K Abe, T Yamagishi, H Iwai… - Analytical and …, 2017 - Springer
Blood adsorption onto the inside surface of hollow fiber dialysis membranes was
investigated by means of time-of-flight secondary ion mass spectrometry (TOF-SIMS) and …

Towards practical time-of-flight secondary ion mass spectrometry lignocellulolytic enzyme assays

RE Goacher, AYL Tsai, ER Master - Biotechnology for biofuels, 2013 - Springer
Abstract Background Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) is a
surface sensitive mass spectrometry technique with potential strengths as a method for …

Image and spectral processing for ToF-SIMS analysis of biological materials

DJ Graham, DG Castner - Mass Spectrometry, 2013 - jstage.jst.go.jp
Time-of-flight secondary ion mass spectrometry (ToF-SIMS) instruments can rapidly produce
large complex data sets. Within each spectrum, there can be hundreds of peaks. A typical …