Precise plant genome editing using base editors and prime editors

KA Molla, S Sretenovic, KC Bansal, Y Qi - Nature Plants, 2021 - nature.com
The development of CRISPR–Cas systems has sparked a genome editing revolution in
plant genetics and breeding. These sequence-specific RNA-guided nucleases can induce …

Genetically modified crops: current status and future prospects

K Kumar, G Gambhir, A Dass, AK Tripathi, A Singh… - Planta, 2020 - Springer
Main conclusion While transgenic technology has heralded a new era in crop improvement,
several concerns have precluded their widespread acceptance. Alternative technologies …

The emerging and uncultivated potential of CRISPR technology in plant science

Y Zhang, AA Malzahn, S Sretenovic, Y Qi - Nature Plants, 2019 - nature.com
The application of clustered regularly interspaced short palindromic repeats (CRISPR) for
genetic manipulation has revolutionized life science over the past few years. CRISPR was …

A multipurpose toolkit to enable advanced genome engineering in plants

T Čermák, SJ Curtin, J Gil-Humanes, R Čegan… - The Plant …, 2017 - academic.oup.com
We report a comprehensive toolkit that enables targeted, specific modification of monocot
and dicot genomes using a variety of genome engineering approaches. Our reagents …

Antioxidants as modulators of arsenic-induced oxidative stress tolerance in plants: An overview

F Zulfiqar, M Ashraf - Journal of Hazardous Materials, 2022 - Elsevier
Arsenic (As) is a highly toxic contaminant in the environment. Although both inorganic and
organic types of arsenic exist in the environment, the most common inorganic forms of As …

Progress and prospects in plant genome editing

K Yin, C Gao, JL Qiu - Nature plants, 2017 - nature.com
The emergence of sequence-specific nucleases that enable genome editing is
revolutionizing basic and applied biology. Since the introduction of CRISPR–Cas9, genome …

Egg cell-specific promoter-controlled CRISPR/Cas9 efficiently generates homozygous mutants for multiple target genes in Arabidopsis in a single generation

ZP Wang, HL Xing, L Dong, HY Zhang, CY Han… - Genome biology, 2015 - Springer
Arabidopsis mutants produced by constitutive overexpression of the CRISPR/Cas9 genome
editing system are usually mosaics in the T1 generation. In this study, we used egg cell …

Molecular recording of mammalian embryogenesis

MM Chan, ZD Smith, S Grosswendt, H Kretzmer… - Nature, 2019 - nature.com
Ontogeny describes the emergence of complex multicellular organisms from single
totipotent cells. This field is particularly challenging in mammals, owing to the indeterminate …

[HTML][HTML] The CRISPR/Cas9 system for plant genome editing and beyond

L Bortesi, R Fischer - Biotechnology advances, 2015 - Elsevier
Targeted genome editing using artificial nucleases has the potential to accelerate basic
research as well as plant breeding by providing the means to modify genomes rapidly in a …

High-frequency, precise modification of the tomato genome

T Čermák, NJ Baltes, R Čegan, Y Zhang, DF Voytas - Genome biology, 2015 - Springer
Background The use of homologous recombination to precisely modify plant genomes has
been challenging, due to the lack of efficient methods for delivering DNA repair templates to …