• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Background Myocardial infarction (MI) is one of the life-threatening coronary-associated
pathologies characterized by sudden cardiac death. The provision of complete insight into …

Background and Purpose: Natriuretic peptides have led the way as a diagnostic and
prognostic tool for the diagnosis and management of heart failure (HF). More recent …

Background Data regarding high-sensitivity troponin concentrations in patients presenting to
the emergency department with symptoms suggestive of myocardial infarction may be useful …

Background: High-sensitivity assays can quantify cardiac troponins I and T (hs-cTnI, hs-
cTnT) in individuals with no clinically manifest myocardial injury. Objectives: The goal of this …

Background: Cardiac troponin is an independent predictor of cardiovascular mortality in
individuals without symptoms or signs of cardiovascular disease. The mechanisms for this …

Aims Our aims were to evaluate the distribution of troponin I concentrations in population
cohorts across Europe, to characterize the association with cardiovascular outcomes, to …

Importance Rapid and accurate diagnosis of acute myocardial infarction (AMI) currently
constitutes an unmet need. Objective To test a 1-hour diagnostic algorithm to diagnose AMI …

Since natriuretic peptides were successfully integrated into the clinical practice of heart
failure (HF), the possibility of using new biomarkers to advance the management of affected …

Measurement of biomarkers has revolutionized the work-up of patients with suspected
cardiovascular disease. The most widely used contemporary cardiovascular biomarkers are …