Recent trends in the use of small extracellular vesicles as optimal drug delivery vehicles in oncology

SK Kumar, MV Sasidhar - Molecular Pharmaceutics, 2023 - ACS Publications
Small extracellular vesicles (sEVs) are produced by most cells and play an important role in
cell-to-cell communication and maintaining cellular homeostasis. Their ability to transfer …

Nanocomposite of chitosan/gelatin/carbon quantum dots as a biocompatible and efficient nanocarrier for improving the Curcumin delivery restrictions to treat brain …

S Ostovar, M Pourmadadi, A Shamsabadipour… - International Journal of …, 2023 - Elsevier
Curcumin (CUR) is among the most appropriate and natural-based anticancer drugs that
can be applied effectively treat different classes of cancers. However, CUR suffers from a …

Plant-derived extracellular vesicles as potential smart nano drug delivery systems for antioxidant vitamins C and E in Alzheimer's disease

A Jiyah, SA Muhammad, A Ibrahim, I Bulama… - Journal of Drug Delivery …, 2024 - Elsevier
The prevalence of Alzheimer's disease is increasing as the aging population and life
expectancy increase. This calls for the development of effective therapeutics with fewer side …

Lactadherin immunoblockade in small extracellular vesicles inhibits sEV-mediated increase of pro-metastatic capacities

E Durán-Jara, M Del Campo, V Gutiérrez… - Biological Research, 2024 - Springer
Background Tumor-derived small extracellular vesicles (sEVs) can promote tumorigenic and
metastatic capacities in less aggressive recipient cells mainly through the biomolecules in …

In Silico Evaluation of Bioactive Compounds of Citrullus lanatus as Potential Noncovalent KRAS Inhibitors in the Treatment of Human Cancer

OE Oyeneyin, N Ipinloju, RA da Costa, TB Adigun… - Chemistry Africa, 2024 - Springer
Cancer deaths and other dangerous symptoms associated with it make the search for
therapies to combat it a necessity. The use of drugs has been implicated in some debilitating …

CD81-guided heterologous EVs present heterogeneous interactions with breast cancer cells

E Gurrieri, G Carradori, M Roccuzzo, M Pancher… - bioRxiv, 2024 - biorxiv.org
Extracellular vesicles (EVs) are cell-secreted particles conceived as natural vehicles for
intercellular communication. The intrinsic biocompatibility, stability in biofluids, and …