EGFR targeting for cancer therapy: Pharmacology and immunoconjugates with drugs and nanoparticles

E da Silva Santos, KAB Nogueira… - International journal of …, 2021 - Elsevier
The epidermal growth factor receptor (EGFR) belongs to the tyrosine kinase receptors family
and is present in the epithelial cell membrane. Its endogenous activation occurs through the …

[HTML][HTML] Male reproductive toxicity of inorganic nanoparticles in rodent models: A systematic review

GPF Dantas, FS Ferraz, LM Andrade… - Chemico-biological …, 2022 - Elsevier
The use of nanoscale materials for different biomedical applications has grown a lot in the
last years and raised several concerns about toxic effects on human health. Several studies …

An overview of essential microelements and common metallic nanoparticles and their effects on male fertility

R Maciejewski, E Radzikowska-Büchner… - International journal of …, 2022 - mdpi.com
Numerous factors affect reproduction, including stress, diet, obesity, the use of stimulants, or
exposure to toxins, along with heavy elements (lead, silver, cadmium, uranium, vanadium …

The role of T-cells in head and neck squamous cell carcinoma: from immunity to immunotherapy

MPS Damasio, CS Nascimento, LM Andrade… - Frontiers in …, 2022 - frontiersin.org
Head and neck squamous cell carcinoma (HNSCC) encompass a group of complex entities
of tumours affecting the aerodigestive upper tract. The main risk factors are strongly related …

Effect of cetuximab-conjugated gold nanoparticles on the cytotoxicity and phenotypic evolution of colorectal cancer cells

R El Hallal, N Lyu, Y Wang - Molecules, 2021 - mdpi.com
Epidermal growth factor receptor (EGFR) is estimated to be overexpressed in 60~ 80% of
colorectal cancer (CRC), which is associated with a poor prognosis. Anti-EGFR targeted …

Gold nanoparticle intratesticular injections as a potential animal sterilization tool: Long-term reproductive and toxicological implications

JLP Coimbra, G de PF Dantas, LM de Andrade… - Toxicology, 2023 - Elsevier
This study aimed to evaluate the gold nanoparticles (AuNPs) animal sterilizing potential after
intratesticular injections and long-term adverse reproductive and systemic effects. Adult …

Epidermal growth factor receptor conjugated fucoidan/alginates loaded hydrogel for activating EGFR/AKT signaling pathways in colon cancer cells during targeted …

K Shanmugapriya, H Kim, HW Kang - International journal of biological …, 2020 - Elsevier
In the present study, we developed epidermal growth factor receptor conjugated
fucoidan/alginate loaded hydrogels for targeting the delivery of hydrogel through the …

Biosynthesis of gold nanoparticles using Kapok (Ceiba pentandra) leaf aqueous extract and investigating their antioxidant activity

A Aji, D Oktafiani, A Yuniarto, AK Amin - Journal of Molecular Structure, 2022 - Elsevier
Ceiba pentandra leaf extracts can be used as a reducing agent and capping agent in the
green synthesis of gold nanoparticles (AuNPs) because it contains phenolic compounds …

The role of different immunocompetent cell populations in the pathogenesis of head and neck cancer—regulatory mechanisms of pro-and anti-cancer activity and their …

K Starska-Kowarska - Cancers, 2023 - mdpi.com
Simple Summary According to the latest GLOBOCAN data, head and neck squamous cell
carcinoma (HNSCC) represents the sixth most prevalent human malignancy. Recent studies …

Multifunctional Hybrid MoS2-PEGylated/Au Nanostructures with Potential Theranostic Applications in Biomedicine

TRS Malagrino, AP Godoy, JM Barbosa, AGT Lima… - Nanomaterials, 2022 - mdpi.com
In this work, flower-like molybdenum disulfide (MoS2) microspheres were produced with
polyethylene glycol (PEG) to form MoS2-PEG. Likewise, gold nanoparticles (AuNPs) were …