A review of the role of flavonoids in peptic ulcer (2010–2020)

C Serafim, ME Araruna, EA Júnior, M Diniz… - Molecules, 2020 - mdpi.com
Peptic ulcers are characterized by erosions on the mucosa of the gastrointestinal tract that
may reach the muscle layer. Their etiology is multifactorial and occurs when the balance …

Garcinia kola: a critical review on chemistry and pharmacology of an important West African medicinal plant

J Tauchen, A Frankova, A Manourova, I Valterova… - Phytochemistry …, 2023 - Springer
Abstract Garcinia kola Heckel (Clusiaceae) is a tree indigenous to West and Central Africa.
All plant parts, but especially the seeds, are of value in local folklore medicine. Garcinia kola …

Amyloid β fibrils disruption by kolaviron: molecular docking and extended molecular dynamics simulation studies

KE Adewole, GA Gyebi, IM Ibrahim - Computational Biology and Chemistry, 2021 - Elsevier
Garcinia kola (GK) produces notable effects against neurodegenerative conditions,
including experimentally-induced Alzheimer's disease (AD). These remarkable effects are …

[HTML][HTML] Kolaviron attenuates cardiovascular injury in fructose-streptozotocin induced type-2 diabetic male rats by reducing oxidative stress, inflammation, and …

JO Adoga, ML Channa, A Nadar - Biomedicine & Pharmacotherapy, 2021 - Elsevier
The prevalence of cardiovascular disease among type-2 diabetic patients has become a
source of major concern world over. This study explored the protective effect of kolaviron, a …

Current status of neuroprotective and neuroregenerative strategies in multiple sclerosis: A systematic review

JR Allanach, JW Farrell III, M Mésidor… - Multiple Sclerosis …, 2022 - journals.sagepub.com
Background: Immune-mediated demyelination and consequent degeneration of
oligodendrocytes and axons are hallmark features of multiple sclerosis (MS). Remyelination …

Cuprizone toxicity and Garcinia kola biflavonoid complex activity on hippocampal morphology and neurobehaviour

GO Omotoso, OJ Olajide, IT Gbadamosi, JO Adebayo… - Heliyon, 2019 - cell.com
Cuprizone-induced neurotoxicity has been employed to study the biology of remyelination in
experimental models of multiple sclerosis. This study was aimed at determining the role of …

Kolaflavanone of kolaviron selectively binds to subdomain 1B of human serum albumin: spectroscopic and molecular docking evidences

AO Kolawole, AN Kolawole, KA Olofinsan… - Computational …, 2020 - Elsevier
Human serum albumin (HSA) is involved in transporting a wide range of therapeutic agents.
This involvement determines the pharmacokinetics and pharmacodynamic properties of the …

D-ribose-L-cysteine modulates paradoxical sleep deprivation-induced neurological impairments: anxiolytic and antioxidative study in rat model

T Abayomi, O Tokunbo, O Oroyemi… - Egyptian Journal of …, 2022 - Taylor & Francis
This study evaluated the anxiolytic and antioxidative potential of DRLC on behavioral
deficits, and neuronal perturbations in the hippocampus following paradoxical sleep …

Kolaviron protects against cognitive deficits and cortico-hippocampal perturbations associated with maternal deprivation in rats

GO Omotoso, NY Mutholib… - Anatomy & Cell …, 2019 - pmc.ncbi.nlm.nih.gov
Prolonged separation of pups from their mother in early postnatal period can interfere with
normal growth and development, resulting in different behavioral changes similar to features …

[PDF][PDF] Garcinia kola: a critical review on chemistry and pharmacology of an important West African medicinal plant

JTAFA Manourova, I Valterova, BLO Leuner - 2023 - academia.edu
Abstract Garcinia kola Heckel (Clusiaceae) is a tree indigenous to West and Central Africa.
All plant parts, but especially the seeds, are of value in local folklore medicine. Garcinia kola …