Gold complexes in anticancer therapy: From new design principles to particle‐based delivery systems

G Moreno‐Alcántar, P Picchetti… - Angewandte Chemie …, 2023 - Wiley Online Library
The discovery of the medicinal properties of gold complexes has fuelled the design and
synthesis of new anticancer metallodrugs, which have received special attention due to their …

Click and bioorthogonal chemistry: the future of active targeting of nanoparticles for nanomedicines?

L Taiariol, C Chaix, C Farre, E Moreau - Chemical Reviews, 2021 - ACS Publications
Over the years, click and bioorthogonal reactions have been the subject of considerable
research efforts. These high-performance chemical reactions have been developed to meet …

Activatable fluorescent probes for real-time imaging-guided tumor therapy

QJ Duan, ZY Zhao, YJ Zhang, L Fu, YY Yuan… - Advanced Drug Delivery …, 2023 - Elsevier
Surgery and drug therapy are the two principal options for cancer treatment. However, their
clinical benefits are hindered by the difficulty of accurate location of the tumors and timely …

Survey of clinical translation of cancer nanomedicines—lessons learned from successes and failures

H He, L Liu, EE Morin, M Liu… - Accounts of chemical …, 2019 - ACS Publications
Conspectus In 1995, the year the first cancer nanomedicine, Doxil, was approved by the
Food and Drug Administration (FDA), only 23 manuscripts appeared in a PubMed search for …

Current trends and challenges in the clinical translation of nanoparticulate nanomedicines: pathways for translational development and commercialization

S Hua, MBC De Matos, JM Metselaar… - Frontiers in …, 2018 - frontiersin.org
The use of nanotechnology in medicine has the potential to have a major impact on human
health for the prevention, diagnosis, and treatment of diseases. One particular aspect of the …

[HTML][HTML] Recent advancements of nanoparticles application in cancer and neurodegenerative disorders: At a glance

MM Rahman, MR Islam, S Akash… - Biomedicine & …, 2022 - Elsevier
Nanoscale engineering is one of the innovative approaches to heal multitudes of ailments,
such as varieties of malignancies, neurological problems, and infectious illnesses …

Metal-free bioorthogonal click chemistry in cancer theranostics

D Wu, K Yang, Z Zhang, Y Feng, L Rao… - Chemical Society …, 2022 - pubs.rsc.org
Bioorthogonal chemistry is a powerful tool to site-specifically activate drugs in living systems.
Bioorthogonal reactions between a pair of biologically reactive groups can rapidly and …

Emerging nanomedicine‐enabled/enhanced nanodynamic therapies beyond traditional photodynamics

H Hu, W Feng, X Qian, L Yu, Y Chen, Y Li - Advanced Materials, 2021 - Wiley Online Library
The rapid knowledge growth of nanomedicine and nanobiotechnology enables and
promotes the emergence of distinctive disease‐specific therapeutic modalities, among …

Precise nanomedicine for intelligent therapy of cancer

H Chen, Z Gu, H An, C Chen, J Chen, R Cui… - Science China …, 2018 - Springer
Precise nanomedicine has been extensively explored for efficient cancer imaging and
targeted cancer therapy, as evidenced by a few breakthroughs in their preclinical and …

Advances and challenges of liposome assisted drug delivery

L Sercombe, T Veerati, F Moheimani, SY Wu… - Frontiers in …, 2015 - frontiersin.org
The application of liposomes to assist drug delivery has already had a major impact on
many biomedical areas. They have been shown to be beneficial for stabilizing therapeutic …