Oxygen (O 2) toxicity remains a concern, particularly to the lung. This is mainly related to
excessive production of reactive oxygen species (ROS). Supplemental O 2, ie inspiratory O …

Surgical site infection (SSI) remains a frequent and challenging complication of surgery. SSI
accounts for greater than 20% of all health care–associated infections, rivaling pneumonia …

Abstract Background In 2016, the World Health Organization (WHO) strongly recommended
the use of a high fraction of inspired oxygen (FiO 2) in adult patients undergoing general …

BACKGROUND: Despite evidence suggesting detrimental effects of perioperative
hyperoxia, hyperoxygenation remains commonplace in cardiac surgery. Hyperoxygenation …

Oxygen administration is particularly relevant in patients undergoing surgery under general
anesthesia and in those who suffer from acute or critical illness. Nevertheless, excess O2, or …

There is an ongoing discussion whether hyperoxia, ie ventilation with high inspiratory O2
concentrations (FIO2), and the consecutive hyperoxaemia, ie supraphysiological arterial O2 …

Study objective Intraoperative lung-protective ventilation strategy has been recommended to
reduce postoperative pulmonary complications (PPCs). However, the role of inspiratory …

Background We aimed to examine whether using a high fraction of inspired oxygen (FIO 2)
in the context of an individualised intra-and postoperative open-lung ventilation approach …

Background It is uncertain whether individualisation of the perioperative open-lung
approach (OLA) to ventilation reduces postoperative pulmonary complications in patients …

Most postoperative surgical patients routinely receive supplemental oxygen therapy to
prevent the potential development of hypoxemia due to incomplete lung re-expansion …