Oxidative stress in cancer therapy: friend or enemy?
M Azmanova, A Pitto‐Barry - Chembiochem, 2022 - Wiley Online Library
Excessive cellular oxidative stress is widely perceived as a key factor in pathophysiological
conditions and cancer development. Healthy cells use several mechanisms to maintain …
conditions and cancer development. Healthy cells use several mechanisms to maintain …
Oxidatively induced DNA damage and its repair in cancer
M Dizdaroglu - Mutation Research/Reviews in Mutation Research, 2015 - Elsevier
Oxidatively induced DNA damage is caused in living organisms by endogenous and
exogenous reactive species. DNA lesions resulting from this type of damage are mutagenic …
exogenous reactive species. DNA lesions resulting from this type of damage are mutagenic …
Urinary 8-hydroxydeoxyguanosine and its analogs as DNA marker of oxidative stress: development of an ELISA and measurement in both bladder and prostate …
CC Chiou, PY Chang, EC Chan, TL Wu, KC Tsao… - Clinica chimica acta, 2003 - Elsevier
Background: 8-hydroxydeoxyguanosine (8-OHdG) is the most frequently detected and
studied DNA lesion. Upon DNA repair, 8-OHdG is excreted in the urine. Urinary 8-OHdG is …
studied DNA lesion. Upon DNA repair, 8-OHdG is excreted in the urine. Urinary 8-OHdG is …
Measurement and meaning of oxidatively modified DNA lesions in urine
Background: Oxidatively generated damage to DNA has been implicated in the
pathogenesis of a wide variety of diseases. The noninvasive assessment of such damage …
pathogenesis of a wide variety of diseases. The noninvasive assessment of such damage …
Products of oxidative DNA damage and repair as possible biomarkers of susceptibility to lung cancer
D Gackowski, E Speina, M Zielinska, J Kowalewski… - Cancer Research, 2003 - AACR
The broad spectrum of oxidative DNA damage biomarkers [urinary excretion of 8-hydroxy-
2′-deoxyguanosine (8-OH-dGuo) and 8-hydroxyguanine (8-OH-Gua)] and the level of …
2′-deoxyguanosine (8-OH-dGuo) and 8-hydroxyguanine (8-OH-Gua)] and the level of …
DNA damage and repair in Alzheimer's disease
F Coppede, L Migliore - Current Alzheimer Research, 2009 - ingentaconnect.com
The vast majority of the studies performed so far and aimed at elucidating DNA repair
mechanisms has been performed in mitotic cells, such as transformed or cancer cell lines …
mechanisms has been performed in mitotic cells, such as transformed or cancer cell lines …
[HTML][HTML] Involvement of oxidatively damaged DNA and repair in cancer development and aging
B Tudek, A Winczura, J Janik, A Siomek… - American journal of …, 2010 - ncbi.nlm.nih.gov
DNA damage and DNA repair may mediate several cellular processes, like replication and
transcription, mutagenesis and apoptosis and thus may be important factors in the …
transcription, mutagenesis and apoptosis and thus may be important factors in the …
Measurement of oxidatively induced DNA damage and its repair, by mass spectrometric techniques
Oxidatively induced damage caused by free radicals and other DNA-damaging agents
generate a plethora of products in the DNA of living organisms. There is mounting evidence …
generate a plethora of products in the DNA of living organisms. There is mounting evidence …
Oxidative DNA damage in cancer patients: a cause or a consequence of the disease development?
A wide variety of oxidative DNA lesions are present in living cells. One of the best known
lesions of this type is 8-oxoguanine (8-oxoGua) which has been shown to have mutagenic …
lesions of this type is 8-oxoguanine (8-oxoGua) which has been shown to have mutagenic …
Lycopene prevents 7-ketocholesterol-induced oxidative stress, cell cycle arrest and apoptosis in human macrophages
P Palozza, R Simone, A Catalano… - The Journal of nutritional …, 2010 - Elsevier
The present study was undertaken to examine whether lycopene is able to counteract 7-
ketocholesterol (7-KC)-induced oxidative stress and apoptosis in human macrophages …
ketocholesterol (7-KC)-induced oxidative stress and apoptosis in human macrophages …