Can advanced-stage ovarian cancer be cured?

S Narod - Nature reviews Clinical oncology, 2016 - nature.com
Approximately 20% of women with advanced-stage ovarian cancer survive beyond 12 years
after treatment and are effectively cured. Initial therapy for ovarian cancer comprises surgery …

[HTML][HTML] A multidisciplinary approach remains the best strategy to improve and strengthen the management of ovarian cancer

L Falzone, G Scandurra… - International …, 2021 - spandidos-publications.com
Ovarian cancer represents one of the most aggressive female tumors worldwide. Over the
decades, the therapeutic options for the treatment of ovarian cancer have been improved …

Invasive epithelial ovarian cancer survival by histotype and disease stage

LC Peres, KL Cushing-Haugen, M Köbel… - JNCI: Journal of the …, 2019 - academic.oup.com
Background The understanding of ovarian cancer pathogenesis has recently shifted to
recognize distinct changes in how ovarian cancer histotypes are defined. Using the 2014 …

Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer

E Sato, SH Olson, J Ahn, B Bundy… - Proceedings of the …, 2005 - National Acad Sciences
In a recent report,[Zhang et al.(2003) N. Engl. J. Med. 348, 203–213], the presence of CD3+
tumor-infiltrating lymphocytes (TILs) was found to correlate with improved survival in …

Bevacizumab and platinum-based combinations for recurrent ovarian cancer: a randomised, open-label, phase 3 trial

J Pfisterer, CM Shannon, K Baumann, J Rau… - The Lancet …, 2020 - thelancet.com
Background State-of-the art therapy for recurrent ovarian cancer suitable for platinum-based
re-treatment includes bevacizumab-containing combinations (eg, bevacizumab combined …

[HTML][HTML] Sensitivity and specificity of multimodal and ultrasound screening for ovarian cancer, and stage distribution of detected cancers: results of the prevalence …

U Menon, A Gentry-Maharaj, R Hallett, A Ryan… - The lancet …, 2009 - thelancet.com
Background Ovarian cancer has a high case–fatality ratio, with most women not diagnosed
until the disease is in its advanced stages. The United Kingdom Collaborative Trial of …

Plasma microRNAs as novel biomarkers for endometriosis and endometriosis-associated ovarian cancer

S Suryawanshi, AM Vlad, HM Lin… - Clinical Cancer …, 2013 - AACR
Purpose: Endometriosis, a largely benign, chronic inflammatory disease, is an independent
risk factor for endometrioid and clear cell epithelial ovarian tumors. We aimed to identify …

[HTML][HTML] Up-regulation of miR-383-5p suppresses proliferation and enhances chemosensitivity in ovarian cancer cells by targeting TRIM27

J Jiang, C Xie, Y Liu, Q Shi, Y Chen - Biomedicine & Pharmacotherapy, 2019 - Elsevier
MicroRNAs are small non-coding RNAs which play important roles in tumor progression.
MiR-383-5p has been characterized as a cancer suppressor in several cancers. The aim of …

Stage at diagnosis and ovarian cancer survival: evidence from the International Cancer Benchmarking Partnership

C Maringe, S Walters, J Butler, MP Coleman… - Gynecologic …, 2012 - Elsevier
OBJECTIVE: We investigate what role stage at diagnosis bears in international differences
in ovarian cancer survival. METHODS: Data from population-based cancer registries in …

A Phase II, open-label study evaluating pazopanib in patients with recurrent ovarian cancer

M Friedlander, KC Hancock, D Rischin, MJ Messing… - Gynecologic …, 2010 - Elsevier
OBJECTIVE: The progression-free and median survival of patients with advanced ovarian
cancer has not appreciably improved over the last decade. Novel targeted therapies …