The prospect of transplanting cells and tissues without the risk of immune rejection or the
need for powerful immunosuppressive drugs is the 'holy grail'of transplantation medicine …

Helminth parasites infect almost one-third of the world's population, primarily in tropical
regions. However, regions where helminth parasites are endemic record much lower …

The three main soil-transmitted helminth infections, ascariasis, trichuriasis, and hookworm,
are common clinical disorders in man. The gastrointestinal tract of a child living in poverty in …

Immunology was founded by studying the body's response to infectious microorganisms,
and yet microbial prokaryotes only tell half the story of the immune system. Eukaryotic …

Strongyloides stercoralis infects 30 million people in 70 countries. Infection usually results in
asymptomatic chronic disease of the gut, which can remain undetected for decades …

Immune regulation by parasites is a global concept that includes suppression, diversion,
and conversion of the host immune response to the benefit of the pathogen. While many …

In the mid-1980s, Mosmann, Coffman, and their colleagues discovered that murine CD4+
helper T-cell clones could be distinguished by the cytokines they synthesized. The isolation …

In this paper we review the published literature on patterns of abundance and aggregation
of macroparasites in wildlife host populations. We base this survey on quantitative analyses …

Schistosome infections are characterized by prominent T cell hyporesponsiveness during
the chronic stage of infection. We found that schistosome-specific phosphatidylserine (PS) …

The major human soil-transmitted helminths (STH), Ascaris lumbricoides, hookworms
(Necator americanus and Ancylostoma duodenale) and Trichuris trichiura have a marked …