Safety, tolerability, and risks associated with first-and second-generation antipsychotics: a state-of-the-art clinical review
M Solmi, A Murru, I Pacchiarotti… - … and clinical risk …, 2017 - Taylor & Francis
Since the discovery of chlorpromazine (CPZ) in 1952, first-generation antipsychotics (FGAs)
have revolutionized psychiatric care in terms of facilitating discharge from hospital and …
have revolutionized psychiatric care in terms of facilitating discharge from hospital and …
Repurposing psychiatric drugs as anti-cancer agents
J Huang, D Zhao, Z Liu, F Liu - Cancer letters, 2018 - Elsevier
Cancer is a major public health problem and one of the leading contributors to the global
disease burden. The high cost of development of new drugs and the increasingly severe …
disease burden. The high cost of development of new drugs and the increasingly severe …
Effects of antipsychotics, antidepressants and mood stabilizers on risk for physical diseases in people with schizophrenia, depression and bipolar disorder
CU Correll, J Detraux, J De Lepeleire… - World …, 2015 - Wiley Online Library
People with severe mental illness have a considerably shorter lifespan than the general
population. This excess mortality is mainly due to physical illness. Next to mental illness …
population. This excess mortality is mainly due to physical illness. Next to mental illness …
Synergistic growth inhibition of HT-29 colon and MCF-7 breast cancer cells with simultaneous and sequential combinations of antineoplastics and CNS drugs
Several central nervous system (CNS) drugs exhibit potent anti-cancer activities. This study
aimed to design a novel model of combination that combines different CNS agents and …
aimed to design a novel model of combination that combines different CNS agents and …
Association of schizophrenia with the risk of breast cancer incidence: a meta-analysis
C Zhuo, PT Triplett - JAMA psychiatry, 2018 - jamanetwork.com
Importance Patients with schizophrenia are considered to have many risk factors for the
development of cancer. However, the incidence of breast cancer in women with …
development of cancer. However, the incidence of breast cancer in women with …
Cancer incidence and stage at diagnosis among people with psychotic disorders: Systematic review and meta-analysis
JC Wootten, JC Wiener, PS Blanchette… - Cancer Epidemiology, 2022 - Elsevier
Research regarding the incidence of cancer among people with psychotic disorders relative
to the general population is equivocal, although the evidence suggests that they have more …
to the general population is equivocal, although the evidence suggests that they have more …
Repurposing antipsychotics of the diphenylbutylpiperidine class for cancer therapy
The recent development of high throughput compound screening has allowed drug
repurposing to emerge as an effective avenue for discovering novel treatments for cancer …
repurposing to emerge as an effective avenue for discovering novel treatments for cancer …
The incidence rate of cancer in patients with schizophrenia: a meta-analysis of cohort studies
Background Numerous studies report that cancer prevalence in patients with schizophrenia
might be different from the general population, but findings remain controversial. Aim Our …
might be different from the general population, but findings remain controversial. Aim Our …
Relationship between prolactin, breast cancer risk, and antipsychotics in patients with schizophrenia: a critical review
M De Hert, J Peuskens, T Sabbe… - Acta Psychiatrica …, 2016 - Wiley Online Library
Objective A recent meta‐analysis showed that breast cancer probably is more common in
female patients with schizophrenia than in the general population (effect size= 1.25, P< …
female patients with schizophrenia than in the general population (effect size= 1.25, P< …