Ice-binding proteins (IBPs) are a diverse class of proteins that assist organism survival in the
presence of ice in cold climates. They have different origins in many organisms, including …

By natural selection, organisms evolve different solutions to cope with extremely cold
weather. The emergence of an antifreeze protein gene is one of the most momentous …

Protein denoising diffusion probabilistic models are used for the de novo generation of
protein backbones but are limited in their ability to guide generation of proteins with …

Two decades have passed since the initial proposition that amyloids are not only (toxic)
byproducts of an unintended aggregation cascade, but that they can also be produced by an …

Protein denoising diffusion probabilistic models (DDPMs) show great promise in the de novo
generation of protein backbones but are limited in their inability to guide generation of …

We report a self-consistent method to translate amino acid sequences into audible sound,
use the representation in the musical space to train a neural network, and then apply it to …

Amyloid fibrils are a pathologically and functionally relevant state of protein folding, which is
generally accessible to polypeptide chains and differs fundamentally from the globular state …

Vaccination has been one of the most successful breakthroughs in medical history. In recent
years, epitope-based subunit vaccines have been introduced as a safer alternative to …

Bacterial ice nucleation proteins (INPs) can cause frost damage to plants by nucleating ice
formation at high sub-zero temperatures. Modeling of Pseudomonas borealis INP by …

Peptide self-assembly is the process by which peptide molecules aggregate into low
dimensional (1D, 2D) or 3D ordered materials with potential applications ranging from drug …