Ice inhibition for cryopreservation: materials, strategies, and challenges

T Chang, G Zhao - Advanced Science, 2021 - Wiley Online Library
Cryopreservation technology has developed into a fundamental and important supporting
method for biomedical applications such as cell‐based therapeutics, tissue engineering …

The promise of organ and tissue preservation to transform medicine

S Giwa, JK Lewis, L Alvarez, R Langer, AE Roth… - Nature …, 2017 - nature.com
The ability to replace organs and tissues on demand could save or improve millions of lives
each year globally and create public health benefits on par with curing cancer. Unmet needs …

The roles of reactive oxygen species and antioxidants in cryopreservation

JS Len, WSD Koh, SX Tan - Bioscience reports, 2019 - portlandpress.com
Cryopreservation has facilitated advancement of biological research by allowing the storage
of cells over prolonged periods of time. While cryopreservation at extremely low …

Improved tissue cryopreservation using inductive heating of magnetic nanoparticles

N Manuchehrabadi, Z Gao, J Zhang, HL Ring… - Science translational …, 2017 - science.org
Vitrification, a kinetic process of liquid solidification into glass, poses many potential benefits
for tissue cryopreservation including indefinite storage, banking, and facilitation of tissue …

Ice-binding proteins and their function

M Bar Dolev, I Braslavsky… - Annual review of …, 2016 - annualreviews.org
Ice-binding proteins (IBPs) are a diverse class of proteins that assist organism survival in the
presence of ice in cold climates. They have different origins in many organisms, including …

Cryopreservation as a key element in the successful delivery of cell-based therapies—a review

J Meneghel, P Kilbride, GJ Morris - Frontiers in medicine, 2020 - frontiersin.org
Cryopreservation is a key enabling technology in regenerative medicine that provides stable
and secure extended cell storage for primary tissue isolates and constructs and prepared …

New approaches to cryopreservation of cells, tissues, and organs

MJ Taylor, BP Weegman, SC Baicu… - Transfusion Medicine and …, 2019 - karger.com
In this concept article, we outline a variety of new approaches that have been conceived to
address some of the remaining challenges for developing improved methods of …

Magnetic iron oxide nanoparticles for disease detection and therapy

S Tong, H Zhu, G Bao - Materials Today, 2019 - Elsevier
Magnetic iron oxide nanoparticles (MIONs) are among the first generation of nanomaterials
that have advanced to clinic use. A broad range of biomedical techniques have been …

Partial freezing of rat livers extends preservation time by 5-fold

SN Tessier, RJ de Vries, CA Pendexter… - Nature …, 2022 - nature.com
The limited preservation duration of organs has contributed to the shortage of organs for
transplantation. Recently, a tripling of the storage duration was achieved with supercooling …

Perfusion, cryopreservation, and nanowarming of whole hearts using colloidally stable magnetic cryopreservation agent solutions

A Chiu-Lam, E Staples, CJ Pepine, C Rinaldi - Science advances, 2021 - science.org
Nanowarming of cryopreserved organs perfused with magnetic cryopreservation agents
(mCPAs) could increase donor organ utilization by extending preservation time and …