Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase
family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis …

Increased levels of tumor necrosis factor (TNF) α have been linked to a number of
pulmonary inflammatory diseases including asthma, chronic obstructive pulmonary disease …

Tumor necrosis factor alpha (TNFα) is the most widely studied pleiotropic cytokine of the
TNF superfamily. In pathophysiological conditions, generation of TNFα at high levels leads …

Asthma is defined as a chronic inflammatory disease of the airways; however, the underlying
physiological and immunological processes are not fully understood. Animal models have …

BACKGROUND: The mechanisms and consequences of the observed association between
obesity and childhood asthma are unclear. OBJECTIVES: We sought to determine the effect …

Asthma is characterized by chronic lower airway inflammation that results in airway
remodeling, which can lead to a permanent decrease in lung function. The pathophysiology …

Outdoor air pollution is one of the leading contributors to adverse respiratory health
outcomes in urban areas around the world. Children are highly sensitive to the adverse …

Background: Asthma and obesity are major public health problems, affecting hundreds of
millions of people worldwide. Obesity is associated with increased asthma risk and severity …

Thymic stromal lymphopoietin (TSLP) is a novel cytokine that triggers dendritic cell-mediated
T helper (Th)-2 inflammatory responses. Previous studies have demonstrated that human …

Isorhamnetin has distinct anti‐inflammatory activity and inhibits cell proliferation and
migration. These effects are also involved in the pathogenesis of asthma. However, the …