PDZ proteins, named for the common structural domain shared by the postsynaptic density
protein (PSD95), Drosophila disc large tumor suppressor (DlgA), and zonula occludens-1 …

α-Latrotoxin (α-LTX) from black widow spider venom induces exhaustive release of
neurotransmitters from vertebrate nerve terminals and endocrine cells. This 130-kDa protein …

Lung alveolar epithelial cells are comprised of type I (ATI) and type II (ATII) cells. AΤΙ cells
are polarized, although they have very flat morphology. The identification of marker proteins …

MAGI-1 is a membrane-associated guanylate kinase protein at tight junctions in epithelial
cells. It interacts with various molecules and functions as a scaffold protein at cell junctions …

The apposed membranes of myelinating Schwann cells are joined by several types of
junctional specializations known as autotypic or reflexive junctions. These include tight, gap …

We recently established the critical role of the lipid phosphatase activity of the PTEN tumor
suppressor in stabilizing cell‐cell contacts and suppressing invasiveness. To delineate the …

In an attempt to find podocyte-expressed proteins that may interact with the tight junction
protein MAGI-1, we screened a glomerulus-enriched cDNA library with a probe consisting of …

While PDZ domain-containing proteins represent cellular targets for several different viral
oncoproteins, including human papillomavirus E6, human T-cell leukemia virus type 1 Tax …

Synaptic scaffolding molecule (S-SCAM) is a synaptic membrane-associated guanylate
kinase with inverted domain organization (MAGI) that interacts with NMDA receptor subunits …

A seven-transmembrane protein, frizzled, has been implicated in a planar cell polarity (PCP)
pathway as well as the canonical Wnt signaling pathway. Although both pathways require a …