Artificial pancreas: past, present, future

C Cobelli, E Renard, B Kovatchev - Diabetes, 2011 - Am Diabetes Assoc
The artificial pancreas (AP), known as closed-loop control of blood glucose in diabetes, is a
system combining a glucose sensor, a control algorithm, and an insulin infusion device. AP …

Diabetes: models, signals, and control

C Cobelli, C Dalla Man, G Sparacino… - IEEE reviews in …, 2009 - ieeexplore.ieee.org
The control of diabetes is an interdisciplinary endeavor, which includes a significant
biomedical engineering component, with traditions of success beginning in the early 1960s …

Electrochemical non-enzymatic glucose sensors: a perspective and an evaluation

KE Toghill, RG Compton - International Journal of electrochemical science, 2010 - Elsevier
An overview of glucose sensors is presented, with specific focus on the promise of non-
enzymatic electrochemical glucose sensors. The review addresses their merits and …

Continuous glucose monitoring and intensive treatment of type 1 diabetes

Juvenile Diabetes Research Foundation … - … England Journal of …, 2008 - Mass Medical Soc
Background The value of continuous glucose monitoring in the management of type 1
diabetes mellitus has not been determined. Methods In a multicenter clinical trial, we …

Biocompatible materials for continuous glucose monitoring devices

SP Nichols, A Koh, WL Storm, JH Shin… - Chemical …, 2013 - ACS Publications
Diabetes mellitus is a worldwide epidemic characterized by chronic hyperglycemia that
results from either a deficiency or tolerance in insulin. 1 In the United States, 8.3% of the …

Manual closed-loop insulin delivery in children and adolescents with type 1 diabetes: a phase 2 randomised crossover trial

R Hovorka, JM Allen, D Elleri, LJ Chassin, J Harris… - The Lancet, 2010 - thelancet.com
Background Closed-loop systems link continuous glucose measurements to insulin delivery.
We aimed to establish whether closed-loop insulin delivery could control overnight blood …

Closed-loop insulin delivery: from bench to clinical practice

R Hovorka - Nature Reviews Endocrinology, 2011 - nature.com
Automated closed-loop insulin delivery, also referred to as the'artificial pancreas', has been
an important but elusive goal of diabetes treatment for many decades. Research milestones …

Clinical performance evaluation of continuous glucose monitoring systems: a scoping review and recommendations for reporting

G Freckmann, M Eichenlaub… - Journal of diabetes …, 2023 - journals.sagepub.com
The use of different approaches for design and results presentation of studies for the clinical
performance evaluation of continuous glucose monitoring (CGM) systems has long been …

The artificial pancreas: How closed-loop control is revolutionizing diabetes

A Haidar - IEEE Control Systems Magazine, 2016 - ieeexplore.ieee.org
The artificial pancreas is a long-awaited goal for the management of type 1 diabetes, and its
development was recently triggered by the development of continuous glucose sensors …

Benefits and limitations of MARD as a performance parameter for continuous glucose monitoring in the interstitial space

L Heinemann, M Schoemaker… - Journal of Diabetes …, 2020 - journals.sagepub.com
High-quality performance of medical devices for glucose monitoring is important for a safe
and efficient usage of this diagnostic option by patients with diabetes. The mean absolute …