A perplexing feature of type 1 diabetes (T1D) is that the immune system destroys pancreatic
β-cells but not neighbouring α-cells, even though both β-cells and α-cells are dysfunctional …

Guidelines have increasingly stressed the concept that adequate glycemic control is
required to prevent or decrease the macro-and microvascular complications of type 2 …

Abstract Originating from Eastern Asia, the plant Cannabis sativa has been used for
centuries as a medicinal treatment. The unwanted psychotropic effects of one of its major …

The prevalence of type-2 diabetes mellitus (T2DM) has increased over 10-fold in the past 40
years in China, which now has the largest T2DM population in the world. Insulin resistance …

Cellular senescence is a response to a wide variety of stressors, including DNA damage,
oncogene activation and physiologic aging, and pathologically accelerated senescence …

There is a need for innovative pharmaceutical intervention in light of the increasing
prevalence of metabolic disease and cardiovascular disease. The kidneys' sodium-glucose …

The rubric of immune-related (ir) diabetes mellitus (DM)(irDM) encompasses various
hyperglycemic disorders related to immune checkpoint inhibitors (ICPis). Beyond sharing …

Type 1 Diabetes (T1D) is a chronic autoimmune disease characterized by a gradual
destruction of insulin-producing β-cells in the endocrine pancreas due to innate and specific …

Alpha cells in the pancreas, traditionally known for their role in secreting glucagon to
regulate blood glucose levels, are gaining recognition for their involvement in the …

Insulin resistance contributes to the development of various diseases, including type 2
diabetes and gestational diabetes. Even though gestational diabetes is specific to …