Microbiome—microbial metabolome—cancer cell interactions in breast cancer—familiar, but unexplored

E Mikó, T Kovács, É Sebő, J Tóth, T Csonka, G Ujlaki… - Cells, 2019 - mdpi.com
Breast cancer is a leading cause of death among women worldwide. Dysbiosis, an aberrant
composition of the microbiome, characterizes breast cancer. In this review we discuss the …

Breast and gut microbiota action mechanisms in breast cancer pathogenesis and treatment

A Laborda-Illanes, L Sanchez-Alcoholado… - Cancers, 2020 - mdpi.com
Simple Summary In this review we discuss the recent knowledge about the role of breast
and gut microbiome in the pathogenesis of breast cancer. We examine the proposed …

A polytherapy based approach to combat antimicrobial resistance using cubosomes

X Lai, ML Han, Y Ding, SH Chow, AP Le Brun… - Nature …, 2022 - nature.com
A depleted antimicrobial drug pipeline combined with an increasing prevalence of Gram-
negative 'superbugs' has increased interest in nano therapies to treat antibiotic resistance …

Mechanisms and Targeted Therapies for Pseudomonas aeruginosa Lung Infection

CS Curran, T Bolig, P Torabi-Parizi - American journal of respiratory …, 2018 - atsjournals.org
Pseudomonas aeruginosa is a complex gram-negative facultative anaerobe replete with a
variety of arsenals to activate, modify, and destroy host defense mechanisms. The microbe is …

[HTML][HTML] Improving therapy of severe infections through drug repurposing of synergistic combinations

YS Cheng, PR Williamson, W Zheng - Current opinion in pharmacology, 2019 - Elsevier
Highlights•Drug combinations improve efficacy and permit dose reductions of each
drug.•Lowering the dose of combined drugs prevents concentration-associated …

Drug repurposing to fight colistin and carbapenem-resistant bacteria

L Peyclit, SA Baron, JM Rolain - Frontiers in Cellular and Infection …, 2019 - frontiersin.org
The emergence of new resistance mechanisms, the failure of classical antibiotics in clinic,
the decrease in the development of antibiotics in the industry are all challenges that lead us …

Pharmaceuticals effect and removal, at environmentally relevant concentrations, from sewage sludge during anaerobic digestion

A Alenzi, C Hunter, J Spencer, J Roberts, J Craft… - Bioresource …, 2021 - Elsevier
This paper investigates the performance of AD in the presence of high-risk pharmaceuticals
found in sewage sludge and its removal capacity. The digestion process of synthetic sewage …

Untapped “-omics”: the microbial metagenome, estrobolome, and their influence on the development of breast cancer and response to treatment

AS Komorowski, RC Pezo - Breast cancer research and treatment, 2020 - Springer
With the advent of next generation sequencing technologies, there is an increasingly
complex understanding of the role of gastrointestinal and local breast microbial dysbiosis in …

Repurposing estrogen receptor antagonists for the treatment of infectious disease

MC Montoya, DJ Krysan - MBio, 2018 - Am Soc Microbiol
The concept of repurposing previously approved medications to the treatment of new
indications by taking advantage of off-target effects has gained traction in recent years …

[HTML][HTML] Tumor-related microbiome in the breast microenvironment and breast cancer

N Wang, T Sun, J Xu - Journal of Cancer, 2021 - ncbi.nlm.nih.gov
Despite the significant progress in diagnosis and treatment over the past years in the
understanding of breast cancer pathophysiology, it remains one of the leading causes of …