The calcium ion (Ca2+) is the simplest and most versatile intracellular messenger known.
The discovery of Ca2+ sparks and a related family of elementary Ca2+ signaling events has …

Ryanodine-sensitive intracellular Ca2+ channels (RyRs) open upon binding Ca2+ at
cytosolic-facing sites. This results in concerted, self-reinforcing opening of RyRs clustered in …

Ca2+ is one of the most important messengers. It transmits signals inside living cells and
takes part in intercellular coordination. The dynamics of the Ca2+ concentration shows a …

Ca 2+ oscillations have been considered to obey deterministic dynamics for almost two
decades. We show for four cell types that Ca 2+ oscillations are instead a sequence of …

We present an information-theoretical analysis of temporal dependencies in EEG microstate
sequences during wakeful rest. We interpret microstate sequences as discrete stochastic …

Intracellular Ca2+ release in many types of cells is mediated by ryanodine receptor Ca2+
release channels (RyRCs) that are assembled into two-dimensional paracrystalline arrays in …

The inositol (1, 4, 5)-trisphosphate receptor (IPR) plays a crucial role in calcium dynamics in
a wide range of cell types, and is often a central feature in quantitative models of calcium …

The ability to distinguish between stochastic systems based on their trajectories is crucial in
thermodynamics, chemistry, and biophysics. The Kullback–Leibler (KL) divergence, D KL AB …

Ca2+ signals, produced by Ca2+ release from cellular stores, switch metabolic responses
inside cells. In muscle, Ca2+ sparks locally exhibit the rapid start and termination of the cell …

We have investigated the subcellular spontaneous Ca2+ events in canine Purkinje cells
using laser scanning confocal microscopy. Three types of Ca2+ transient were found:(1) …