One of the leading causes of morbidity and premature mortality in older people is frailty.
Frailty occurs when multiple physiological systems decline, to the extent that an individual's …

Orthogeriatrics is increasingly recommended in the care of hip fracture patients, although
evidence for this model is conflicting or at least limited. Furthermore, there is no conclusive …

Muscles and bones are intricately connected tissues displaying marked co-variation during
development, growth, aging, and in many diseases. While the diagnosis and treatment of …

Background Optimal vitamin D intake and its status are important not only for bone and
calcium-phosphate metabolism, but also for overall health and well-being. Vitamin D …

Given the progressive ageing of Western populations, the fragility fractures market has a
growing socioeconomic impact. Fragility fractures are common in the elderly, negatively …

Background Frailty is an aging syndrome caused by exceeding a threshold of decline across
multiple organ systems leading to a decreased resistance to stressors. Treatment for frailty …

The reduced muscle mass and impaired muscle performance that define sarcopenia in older
individuals are associated with increased risk of physical limitation and a variety of chronic …

Background One of the major threats looming over the growing older population is frailty. It is
a distinctive health state characterised by increased vulnerability to internal and external …

Sex steroids are chief regulators of gender differences in the skeleton, and male gender is
one of the strongest protective factors against osteoporotic fractures. This advantage in bone …

Objectives Both sarcopenia and physical frailty are geriatric syndromes causing loss of
functionality and independence. This study explored the association between sarcopenia …