Nausea and vomiting are common gastrointestinal complaints that can be triggered by
diverse emetic stimuli through central and/or peripheral nervous systems. Both nausea and …

Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), the responsible agent for
the coronavirus disease 2019 (Covid-19), has its entry point through interaction with …

Abstract Glycogen synthase kinase 3 (GSK-3) is a constitutively active multifunctional serine-
threonine kinase which is involved in diverse physiological processes. GSK-3 has been …

Polyamine conjugated flavonoid with a naphthalene moiety (ZYY14) displayed excellent
therapeutic activity against hepatocellular carcinoma. In this study, three different series of …

BJOC - Construction of trisubstituted chromone skeletons carrying electron-withdrawing
groups via PhIO-mediated dehydrogenation and its application to the synthesis of frutinone A …

Nausea and vomiting are often considered as stressful symptoms of many diseases and
drugs. In fact they are the most feared and debilitating side-effects of many cancer …

Nausea and vomiting are protective defense mechanisms by which vomit competent species
avoid ingestion of potentially toxic substances. More specifically, vomiting is the act of …

We previously reported that sevoflurane-induced pica, kaolin ingestion behavior, in rats has
the potential to reflect postoperative nausea and vomiting (PONV) in humans. It is well …

Cisplatin-like chemotherapeutics cause vomiting via calcium (Ca2+)-dependent release of
multiple neurotransmitters/mediators (dopamine, serotonin, substance P, prostaglandins …

This mini-review summarizes our recent published findings on the: i) emetic potential of
cysteinyl leukotrienes LTC4, LTD4 and LTE4 in the least shrew (Cryptotis parva) model of …