Modeling diet‐induced metabolic syndrome in rodents

BF Leonardi, G Gosmann… - Molecular Nutrition & Food …, 2020 - Wiley Online Library
Standardized animal models represent one of the most valuable tools available to
understand the mechanism underlying the metabolic syndrome (MetS) and to seek for new …

Systematic review of polyherbal combinations used in metabolic syndrome

AH Palla, F Amin, B Fatima, A Shafiq… - Frontiers in …, 2021 - frontiersin.org
Background: Metabolic syndrome (MetS) is a multifactorial disease, whose main stay of
prevention and management is life-style modification which is difficult to attain. Combination …

Repositioning of clinically approved drug Bazi Bushen capsule for treatment of Aizheimer's disease using network pharmacology approach and in vitro experimental …

T Wang, M Chen, H Li, G Ding, Y Song, B Hou, B Yao… - Heliyon, 2023 - cell.com
Aims To explore the new indications and key mechanism of Bazi Bushen capsule (BZBS) by
network pharmacology and in vitro experiment. Methods The ingredients library of BZBS …

[PDF][PDF] Natural products repurposing of the H5N1-based lead compounds for the most fit inhibitors against 3C-like protease of SARS-CoV-2

AA Parikesit, R Nurdiansyah… - J Pharm Pharmacogn …, 2021 - researchgate.net
Resumen Context: COVID-19 pandemic has caused more than 2.7 million mortality
worldwide. Although the COVID-19 vaccine has been developed, the amount is still limited …

Ethanol extract of Pharbitis nil ameliorates liver fibrosis through regulation of the TGFβ1-SMAD2/3 pathway

HJ Jung, K Cho, SY Kim, JK Seong, SH Oh - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Pharbitis nil (L.) Choisy is a medicinal herb, and herbal
remedies based on its seeds have been used to treat of obesity and liver diseases, including …

Novel topical anandamide formulation for alleviating peripheral neuropathic pain

A Police, VK Shankar, P Pandey, S Rangappa… - International Journal of …, 2023 - Elsevier
Peripheral neuropathy (PN) is a condition of peripheral nerve damage leading to severe
pain. The first line therapies are associated with adverse psychotropic effects (PSE) and …

Network pharmacology predicts combinational effect of novel herbal pair consist of Ephedrae herba and Coicis semen on adipogenesis in 3T3-L1 cells

DW Lim, GR Yu, JE Kim, WH Park - Plos one, 2023 - journals.plos.org
Background Herbal combinations are regarded as basic strategy in oriental medicine with
various purposes. Ephedrae herba (EH) and Coicis semen (CS) are two herbal medicines …

Literature‐based drug repurposing in traditional Chinese medicine: reduced inflammatory M1 macrophage polarization by Jisil Haebaek Gyeji‐Tang alleviates …

GR Yu, SJ Lee, DH Kim, DW Lim, H Kim… - Evidence‐Based …, 2020 - Wiley Online Library
Relatively high proportions of proinflammatory M1‐like macrophages in tissues may lead to
vascular impairment and trigger numerous diseases including atherosclerosis‐related …

Antimicrobial compounds from an FDA‐approved drug library with activity against Streptococcus suis

H Li, T Li, L Zhang, Q Hu, X Liao, Q Jiang… - Journal of Applied …, 2022 - academic.oup.com
Aim Antimicrobial resistance (AMR) has become a global concern. Developing novel
antimicrobials is one of the most effective approaches in tackling AMR. Considering its …

Verification of the Potential Targets of the Herbal Prescription Sochehwan for Drug Repurposing Processes as Deduced by Network Pharmacology

DW Lim, DH Kim, GR Yu, WH Park, JE Kim - Processes, 2021 - mdpi.com
Network pharmacology (NP) is a useful, emerging means of understanding the complex
pharmacological mechanisms of traditional herbal medicines. Sochehwan (SCH) is a …