Septic shock is mainly characterized—in addition to hypovolemia—by vasoplegia as a
consequence of a release of inflammatory mediators. Systemic vasodilatation due to …

Arginine Vasopressin (AVP) is one of the key hormones in the human body. AVP is clinically
important because it maintains body fluid balance and vascular tone. Unfortunately, AVP …

Copeptin derives from the same precursor peptide preprovasopressin as arginine
vasopressin (AVP). The secretion of both peptides is stimulated by similar physiological …

OBJECTIVES: To identify research priorities in the management, epidemiology, outcome,
and pathophysiology of sepsis and septic shock. DESIGN: Shortly after publication of the …

Septic shock management in the cardiac intensive care unit (CICU) is challenging due to the
complex interaction of pathophysiology between vasodilatory and cardiogenic shock …

Background. This retrospective study examines the relationship between admission Blood
Urea Nitrogen (BUN) levels and clinical outcomes in patients with sepsis from two separate …

Copeptin is a 39-amino acid glycopeptide that is secreted equimolecularly with arginine-
vasopressin (AVP) from the prepro-hormone AVP in the posterior pituitary. While AVP is a …

Background: Stroke is the second main cause of mortality and the third leading cause of
mortality and permanent disability combined. Many potential biomarkers have been …

The serum biomarker copeptin, an innovative and stable substitute biomarker of
vasopressin, is associated with stroke. Therefore, establishing a highly sensitive time …

Objective: Systemic infections and sepsis lead to a strong activation of the vasopressin
system, which is pivotal for stimulation of the endocrine stress response and in addition has …